Results 81 to 90 of about 15,407,870 (296)

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

NEUTRAL EVOLUTION: A NULL MODEL FOR LANGUAGE DYNAMICS [PDF]

open access: yesAdvances in Complex Systems, 2012
We review the task of aligning simple models for language dynamics with relevant empirical data, motivated by the fact that this is rarely attempted in practice despite an abundance of abstract models. We propose that one way to meet this challenge is through the careful construction of null models. We argue in particular that rejection of a null model
openaire   +5 more sources

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

How do plant communities and flower visitors relate? A case study of semi-natural xerothermic grasslands

open access: yesActa Societatis Botanicorum Poloniae, 2013
The paper examines the relationships between the species composition of flower visitors and plants in the semi-natural xerothermic grasslands in southern and central Poland.
Damian Chmura   +2 more
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

open access: yesFEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen   +5 more
wiley   +1 more source

Species assemblages of zooplanktonic crustaceans in mountain shallow ponds of Chile (Parque Cañi)

open access: yesZoologia (Curitiba), 2010
Even though the Chilean lakes are characterized by their oligotrophy, a transition from oligotrophy to mesotrophy, due human intervention, has been reported in some lakes.
Patricio De los Ríos, Guido Roa
doaj   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

open access: yesFEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima   +7 more
wiley   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

Modeling: Neutral, Null, and Baseline [PDF]

open access: yesPhilosophy of Science, 2018
Two strategies for using a model as “null” are distinguished.Null modelingevaluates whether a process is causally responsible for a pattern by testing it against a null model.Baseline modelingmeasures the relative significance of various processes responsible for a pattern by detecting deviations from a baseline model.
openaire   +1 more source

Mechanisms of bacterial and fungal community assembly in leaf miners during transition from natural to laboratory environments

open access: yesFrontiers in Microbiology
Environmental heterogeneity partly drives microbial succession in arthropods, while the microbial assembly mechanisms during environmental changes remain largely unknown.
Yu-Xi Zhu   +5 more
doaj   +1 more source

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