Results 61 to 70 of about 15,407,870 (296)

The architecture of antagonistic networks: Node degree distribution, compartmentalization and nestedness [PDF]

open access: yesComputational Ecology and Software, 2015
Describing complex ecosystems as networks of interacting components has proved fruitful - revealing many distinctive patterns and dynamics of ecological systems.
Savannah Nuwagaba, Cang Hui
doaj  

Using Model Analysis to Unveil Hidden Patterns in Tropical Forest Structures

open access: yesFrontiers in Ecology and Evolution, 2021
When ordinating plots of tropical rain forests using stand-level structural attributes such as biomass, basal area and the number of trees in different size classes, two patterns often emerge: a gradient from poorly to highly stocked plots and high ...
Nicolas Picard   +18 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

open access: yesFEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual   +3 more
wiley   +1 more source

The Mid-Domain Effect Shapes a Unimodal Latitudinal Pattern in Fruiting Phenology

open access: yesPlants
The mid-domain effect (MDE) has been used to explain spatial diversity patterns and flowering phenology, but its role in fruiting phenology has received limited attention to date.
Longyang Zhang, Qianhuai Xue, Yanjun Du
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Supply–demand governance of hierarchical healthcare systems: mobile big data unveils non-random patient flow patterns and the bypass premium in cities

open access: yesFrontiers in Public Health
BackgroundThe uneven distribution of healthcare resources and jobs-housing spatial separation are reshaping the spatiotemporal patterns of urban patient flows.
Qing Guo   +3 more
doaj   +1 more source

An index for measuring functional extension and evenness in trait space

open access: yesEcology and Evolution, 2021
Most existing functional diversity indices focus on a single facet of functional diversity. Although these indices are useful for quantifying specific aspects of functional diversity, they often present some conceptual or practical limitations in ...
Tao Zhang   +3 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Macrophytes assemblages in mountain lakes of Huerquehue National Park (39°S, Araucanía Region, Chile) Ensambles de macrófitas en lagos de montaña del Parque Nacional Huerquehue (39°S, Región de la Araucanía, Chile)

open access: yesLatin American Journal of Aquatic Research, 2011
The lakes studied (Tinquilco, Verde, Toro, Chico) are located in the Huerquehue National Park (39°08'S, 71°40'W), Chile. An inventory of the aquatic and riparian species was performed between December 2005 and March 2006.
Enrique Hauenstein   +2 more
doaj  

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