Results 61 to 70 of about 22,265,852 (345)
The “Null-A” superintegrability for monomial matrix models
Annals of Physics, 2023 We find that superintegrability (character expansion) property persists in the exotic sector of the monomial non-Gaussian matrix model, with potential $\Tr X^r$, in pure phase, where the naive partition function $\langle 1 \rangle$ vanishes. The role of the (anomaly-corrected) partition function is played by $\left\langleχ_ρ\right\rangle$ -- the Schur ...
Barseghyan, S., Popolitov, A.
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Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
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A matrix model for the null-brane [PDF]
Journal of High Energy Physics, 2006 26 pages, LaTeX; references ...
Robbins, Daniel, Sethi, Savdeep
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The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
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An index for measuring functional extension and evenness in trait space
Ecology and Evolution, 2021 Most existing functional diversity indices focus on a single facet of functional diversity. Although these indices are useful for quantifying specific aspects of functional diversity, they often present some conceptual or practical limitations in ...
Tao Zhang +3 more
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Modeling: Neutral, Null, and Baseline [PDF]
Philosophy of Science, 2018 Two strategies for using a model as “null” are distinguished.Null modelingevaluates whether a process is causally responsible for a pattern by testing it against a null model.Baseline modelingmeasures the relative significance of various processes responsible for a pattern by detecting deviations from a baseline model.
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FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Bird species diversity in the Atlantic Forest of Brazil is not explained by the Mid-domain Effect
Zoologia (Curitiba), 2012 The Atlantic Forest is an excellent case study for the elevational diversity of birds, and some inventories along elevational gradients have been carried out in Brazil.
Vagner Cavarzere, Luís Fábio Silveira
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FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
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