Results 41 to 50 of about 512,275 (295)
Filaggrin null mutations are associated with atopic dermatitis and elevated levels of IgE in the Japanese population: a family and case–control study [PDF]
, 2008 Filaggrin (FLG) plays an important role in the barrier function of the skin. Several loss-of-function mutations in the FLG gene have been identified in patients with ichthyosis vulgaris, and these null mutations are associated with atopic dermatitis (AD)
Arinami Tadao +14 more
core +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
What May Statistics Tell Us About Null Subjects in Russian?
Вестник Волгоградского государственного университета: Серия 2. Языкознание, 2022 The article highlights the linguistic phenomenon of abandoning the expletively presented syntactic subject (the Null Subject Phenomenon) in different languages and focuses on its exemplification by the Russian language.
Polina Eismont
doaj +1 more source
Register variation, truncation, and subject omission in English and in French [PDF]
, 2017 This paper concerns the null subject phenomenon attested in abbreviated written registers in English and in French (diaries, instructions) and in informal spoken English.
Haegeman, Liliane
core
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Null subjects in european and Brasilian Portuguese [PDF]
, 2005 The goals of this paper are twofold: a) to provide a structural account of the effects of the informal ‘Avoid Pronoun Principle’, proposed in Chomsky (1981: 65) for the Null Subject Languages (NSLs), and b) to compare, in European and Brazilian ...
Barbosa, Pilar +2 more
core
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Isogloss, 2019 There is an on-going debate on the empirical adequacy of the movement approach to definite null subjects in Brazilian Portuguese, BP (cf. Ferreira 2000, Rodrigues 2004, and Nunes 2009).
Claudia Coelho +2 more
doaj +3 more sources
Spanish null subjects: descriptive and analytical issues
Borealis: An International Journal of Hispanic LinguisticsThe goal of this article is to present a detailed overview of the empirical patterns concerning null subjects in Spanish, and the theories that have been proposed to account for them.
Antonio Fábregas
doaj +1 more source
BMC Medical Genetics, 2020 Background Glutathione S-transferases play a key role in the detoxification of persistent oxidative stress products which are one of several risks factors that may be associated with many types of disease processes such as cancer, diabetes, and ...
Herman Karim Sombié +16 more
doaj +1 more source