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Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
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Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Why do we differ in number sense? Evidence from a genetically sensitive investigation.
Intelligence, 2014 Tosto MG +11 more
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A sense of number in invertebrates
Biochemical and Biophysical Research Communications, 2021Non-symbolic numerical abilities are widespread among vertebrates due to their important adaptive value. Moreover, these abilities were considered peculiar of vertebrate species as numerical competence is regarded as cognitively sophisticated. However, recent evidence convincingly showed that this is not the case: invertebrates, with their limited ...
Bortot, Maria +2 more
openaire +4 more sources
Feeling number: grounding number sense in a sense of quantity
Educational Studies in Mathematics, 2010Drawing on results from psychology and from cultural and linguistic studies, we argue for an increased focus on developing quantity sense in school mathematics. We explore the notion of “feeling number”, a phrase that we offer in a twofold sense—resisting tendencies to feel numb-er (more numb) by developing a feeling for numbers and the quantities they
David Wagner, Brent Davis
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The Journal of Special Education, 1999
We describe the concept of number sense, an analog as important to mathematics learning as phonemic awareness has been to the reading research field. Understanding the concept of number sense and relevant research from cognitive science can help the research community pull together fragmented pieces of earlier knowledge to yield a much richer, more ...
Russell Gersten, David Chard
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We describe the concept of number sense, an analog as important to mathematics learning as phonemic awareness has been to the reading research field. Understanding the concept of number sense and relevant research from cognitive science can help the research community pull together fragmented pieces of earlier knowledge to yield a much richer, more ...
Russell Gersten, David Chard
openaire +1 more source
Behavioral and Brain Sciences, 2017
AbstractNumerosity is inherently confounded by related stimulus attributes such as density and area, and many studies have reported interactions of various strengths between area, density, and numerosity. However, direct measurements of sensitivity within the area-density-numerosity space show that numerosity emerges as the most spontaneous and ...
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AbstractNumerosity is inherently confounded by related stimulus attributes such as density and area, and many studies have reported interactions of various strengths between area, density, and numerosity. However, direct measurements of sensitivity within the area-density-numerosity space show that numerosity emerges as the most spontaneous and ...
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Journal of Learning Disabilities, 2005
Drawing on various approaches to the study of mathematics learning, Gersten, Jordan, and Flojo (in this issue) explore the implications of this research for identifying children at risk for developing mathematical disabilities. One of the key topics Gersten et al.
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Drawing on various approaches to the study of mathematics learning, Gersten, Jordan, and Flojo (in this issue) explore the implications of this research for identifying children at risk for developing mathematical disabilities. One of the key topics Gersten et al.
openaire +2 more sources
2018
In this activity, students demonstrate their own innate number sense by playing an online game that asks them to estimate quantities that are flashed on screen for only milliseconds.
Fleming-Davies, Arietta, Wojdak, Jeremy
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In this activity, students demonstrate their own innate number sense by playing an online game that asks them to estimate quantities that are flashed on screen for only milliseconds.
Fleming-Davies, Arietta, Wojdak, Jeremy
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The Mathematics Teacher, 1988
Good number sense is fundamental for success in estimation, approximation, and problem solving. We need to develop a sense of large numbers because newspaper and television news reports contain many references to large quantities. The federal budget is expressed in billions and trillions of dollars, space distances in millions of light years or ...
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Good number sense is fundamental for success in estimation, approximation, and problem solving. We need to develop a sense of large numbers because newspaper and television news reports contain many references to large quantities. The federal budget is expressed in billions and trillions of dollars, space distances in millions of light years or ...
openaire +1 more source