Results 101 to 110 of about 7,693,267 (324)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Asymptotics of the Eigenvalues of a Self-Adjoint Fourth Order Boundary Value Problem with Four Eigenvalue Parameter Dependent Boundary Conditions

open access: yesJournal of Function Spaces and Applications, 2013
Considered is a regular fourth order ordinary differential equation which depends quadratically on the eigenvalue parameter λ and which has separable boundary conditions depending linearly on λ.
Manfred Möller, Bertin Zinsou
doaj   +1 more source

Combinatorial and Additive Number Theory Problem Sessions: '09--'19

open access: yes, 2019
These notes are a summary of the problem session discussions at various CANT (Combinatorial and Additive Number Theory Conferences). Currently they include all years from 2009 through 2019 (inclusive); the goal is to supplement this file each year. These
Miller, Steven J.
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

The Hybrid Power Mean of Sixth Gauss Sums and the Two-Term Exponential Sums

open access: yesJournal of Applied Mathematics
The principal aim of this paper is to analyze the hybrid power mean value of sixth Gauss sums and two-term exponential sums. It will use various analytic methods and elementary methods to develop unique identities for these types of sums.
Xuan Wang
doaj   +1 more source

Finite groups in Axiomatic Index Number Theory [PDF]

open access: yes
In this paper we adopt Group Theory to investigate the symmetry and invariance properties of price index numbers. An alternative treatment is given to the study of the reversibilty axioms, that clarifies their meaning and allows for a conceptual ...
Marco Fattore
core  

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