Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Heterogeneity in mathematics: Investigating cognitive profiles and reading comorbidities among children. [PDF]
Hasson S, Ashkenazi S.
europepmc +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
The cognitive processing of numerical bases: a review of empirical evidence. [PDF]
Göbel SM, Inglis M, Bahnmueller J.
europepmc +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
An integrated workflow for the structure elucidation of nanocrystalline powders. [PDF]
Sabena C +9 more
europepmc +1 more source
Finiteness property in Cantor real numeration systems
For alternate Cantor real base numeration systems we generalize the result of Frougny and~Solomyak on~arithmetics on the set of numbers with finite expansion. We provide a class of alternate bases which satisfy the so-called finiteness property.
Masáková, Zuzana +2 more
core
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
The notion of the numeral base in linguistics. [PDF]
Barlow R.
europepmc +1 more source
Hazards&Robots: A dataset for visual anomaly detection in robotics. [PDF]
Mantegazza D +4 more
europepmc +1 more source

