Results 61 to 70 of about 1,107 (197)

Mini-symposium on automatic differentiation and its applications in the financial industry

ESAIM: Proceedings and Surveys, 2017
Automatic differentiation has been involved for long in applied mathematics as an alternative to finite difference to improve the accuracy of numerical computation of derivatives.
Geeraert Sébastien, Lehalle Charles-Albert, Pearlmutter Barak A., Pironneau Olivier, Reghai Adil   +4 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

A Richardson’s Extrapolation Spreadsheet Calculator for Numerical Differentiation

Spreadsheets in Education, 2013
Even though approximating the definite differentiation by Richardson’s extrapolation method is straight forward, but its repetitive calculations are quite boring. Hence, there is a need to develop a suitable tool in teaching and learning for this method.
Kim Gaik Tay, Sie Long Kek, Rosmila Abdul-Kahar, Mohd Azwir Azlan, Ming Foong Lee   +4 more
doaj   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Numerical Differentiation and Integration through Aitken-Neville Schemes

International Journal of Analysis and Applications, 2013
Some new formulas are given to approximate higher order derivatives and integrals through Aitken-Neville iterative schemes for arbitrary spaced grids. An algorithm is given in MATLAB for numerical differentiation. Also, numerical examples are provided to
Ramesh Kumar Muthumalai
doaj   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Computing the Dirichlet-to-Neumann map via an integral equation with the adjoint generalized Neumann kernel

Partial Differential Equations in Applied Mathematics
A new numerical method for computing the Dirichlet-to-Neumann map for Laplace’s equation in simply and multiply connected smooth domains is introduced. This method is based on an integral equation with the adjoint generalized Neumann kernel.
Samir Naqos, Ali H.M. Murid, Mohamed M.S. Nasser, Su Hoe Yeak   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source