Results 61 to 70 of about 473,529 (307)
MathematicsIterative methods for solving constraint nonlinear monotone equations have been developed and improved by many researchers. The aim of this research is to present a modified three-term conjugate descent (TTCD) derivative-free method for constrained ...
Aliyu Yusuf +2 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
AxiomsThis study proposes a dimensionality reduction method based on proper orthogonal decomposition (POD) for numerically solving the Schrödinger equation by optimizing the coefficient vectors of the Crank–Nicolson finite element (CNFE) solution.
Xiaohui Chang +3 more
doaj +1 more source
Analysis of dynamic wave model for flood routing in natural rivers
Water Science and Engineering, 2012 Flooding is a common natural disaster that causes enormous economic, social, and human losses. Of various flood routing methods, the dynamic wave model is one of the best approaches for the prediction of the characteristics of floods during their ...
Reza Barati +2 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
CoastsThe aim of this work was to investigate the evolutionary mechanisms of an artificial sedimentary agglomerate formed by cathodic polarization in natural seawater during its abandonment to a natural environment.
Louis Zadi +6 more
doaj +1 more source
Towards the Optimal Design of Numerical Experiments [PDF]
IEEE Transactions on Neural Networks, 2008 This paper addresses the problem of the optimal design of numerical experiments for the construction of nonlinear surrogate models. We describe a new method, called learner disagreement from experiment resampling (LDR), which borrows ideas from active learning and from resampling methods: the analysis of the divergence of the predictions provided by a ...
Gazut, Stéphane +3 more
openaire +3 more sources
Numerical experiments of data sizes.
, 2023 Numerical experiments of data sizes.
Xiqun (Michael) Chen (14439203) +3 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Performance of Adaptive Unstructured Mesh Modelling in Idealized Advection Cases over Steep Terrains
Atmosphere, 2018 Advection errors are common in basic terrain-following (TF) coordinates. Numerous methods, including the hybrid TF coordinate and smoothing vertical layers, have been proposed to reduce the advection errors.
Jinxi Li +7 more
doaj +1 more source