Results 151 to 160 of about 209,471 (303)

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Numerical Integration

open access: yes, 1997
This article describes classical quadrature methods and, more briefly, some of the more advanced methods for which software is widely available. The description of the elementary methods in this article borrows from introductory notes by Stewart [31]. An
Gordon K. Smyth
core  

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

A graphical approach to integration and the fundamental theorem [PDF]

open access: yes
In ‘Understanding the Calculus’ 3 I suggested how the concepts of the calculus could be approached globally using moving computer graphics. The idea of area under a graph presents a fundamentally greater problem than that of the notion of gradient. Each
Tall, David
core  

A Cardiovascular Model Based on Finite Element Method and Electrical Analog Model

open access: yes工程科学与技术, 2012
:An anisotropic left ventricular (LV) model was composed by non-linear finite element method to relate regional ischemic effect of the LV to the global cardiovascular system.
doaj  

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

A Simplified Numerical Integration Format of Newmark-β Method for Structural Dynamic Equations

open access: yes工程科学与技术, 2008
:On the basis of Newmark-β method and superpasition principle, a new simplified numerical integration format for structural dynamics is deducted. The method is simple and convenient for elastic plastic seismic response analysis because its calculated ...
doaj  

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