Results 61 to 70 of about 337,061 (308)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

On the Singularity of Multivariate Hermite Interpolation of Total Degree

open access: yesDiscrete Dynamics in Nature and Society, 2016
We study the singularity of multivariate Hermite interpolation of type total degree on m nodes with 3 ...
Zhongyong Hu   +2 more
doaj   +1 more source

The INTERNODES method for the treatment of non-conforming multipatch geometries in Isogeometric Analysis

open access: yes, 2019
In this paper we apply the INTERNODES method to solve second order elliptic problems discretized by Isogeometric Analysis methods on non-conforming multiple patches in 2D and 3D geometries.
Gervasio, Paola, Marini, Federico
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Numerical convergence of nonlinear nonlocal continuum models to local elastodynamics

open access: yes, 2018
We quantify the numerical error and modeling error associated with replacing a nonlinear nonlocal bond-based peridynamic model with a local elasticity model or a linearized peridynamics model away from the fracture set. The nonlocal model treated here is
Jha, Prashant K., Lipton, Robert
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Error Analysis of Higher Order Bivariate Lagrange and Triangular Interpolations in Electromagnetics

open access: yesIEEE Open Journal of Antennas and Propagation, 2020
The interpolation errors of the higher order bivariate Lagrange polynomial interpolation based on the rectangular, right and equilateral triangular interpolations are measured by using the maximum and root-mean-square (RMS) errors.
Wen Luo   +3 more
doaj   +1 more source

On Transmit Beamforming for MISO-OFDM Channels With Finite-Rate Feedback

open access: yes, 2015
With finite-rate feedback, we propose two feedback methods for transmit beamforming in a point-to-point MISO-OFDM channel. For the first method, a receiver with perfect channel information, quantizes and feeds back the optimal transmit beamforming ...
Mamat, Kritsada, Santipach, Wiroonsak
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Empirical mode decomposition with shape-preserving spline interpolation

open access: yesResults in Applied Mathematics, 2020
Empirical mode decomposition (EMD) is a popular, novel, user-friendly algorithm to decompose a given signal into its constituting components, utilizing spline interpolation.
Maria D. van der Walt
doaj   +1 more source

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