Results 41 to 50 of about 338,637 (278)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Numerical treatments for a multi-time delay complex order mathematical model of HIV/AIDS and malaria
Alexandria Engineering Journal, 2022 In this artical, we present a novel complex order nonlinear mathematical model of HIV/AIDS and Malaria co-infection with multi-delay. The proposed model is formulated as a system of twelve complex order differential equations.
N.H. Sweilam +2 more
doaj +1 more source
Stochastic methods for solving high-dimensional partial differential equations
, 2018 We propose algorithms for solving high-dimensional Partial Differential Equations (PDEs) that combine a probabilistic interpretation of PDEs, through Feynman-Kac representation, with sparse interpolation.
A Cohen +10 more
core +3 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Another Six-Node Triangular Element for Structural Analysis
Engineering Transactions, 2022 A six-node triangular element is presented in this paper for structural analysis. With this approach, the approximation functions of the interpolation strategy are given by using the double interpolation procedure, which includes nodal values as well as ...
Lan HOANG THAT TON
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Polynomial-Based Non-Uniform Ternary Interpolation Surface Subdivision on Quadrilateral Mesh
Mathematics, 2023 For non-uniform control polygons, a parameterized four-point interpolation curve ternary subdivision scheme is proposed, and its convergence and continuity are demonstrated.
Kaijun Peng, Jieqing Tan, Li Zhang
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
, 2018 We present an effective harmonic density interpolation method for the numerical evaluation of singular and nearly singular Laplace boundary integral operators and layer potentials in two and three spatial dimensions. The method relies on the use of Green'
Faria, Luiz M. +2 more
core +3 more sources