Results 41 to 50 of about 30,800 (259)
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Polynomial-Based Non-Uniform Ternary Interpolation Surface Subdivision on Quadrilateral Mesh
For non-uniform control polygons, a parameterized four-point interpolation curve ternary subdivision scheme is proposed, and its convergence and continuity are demonstrated.
Kaijun Peng, Jieqing Tan, Li Zhang
doaj +1 more source
Interpolation inequalities of numerical radius
Summary: In this paper, we give several generalization and refinement of numerical radius inequalities of bounded linear operators on a complex Hilbert space. It is shown that the bounds obtained here are stronger than the known bounds of numerical radius inequalities.
openaire +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Numerical continued fraction interpolation
UDC 517.524 We show that highly accurate approximations can often be obtained by constructing Thiele interpolating continued fractions by a Greedy selection of the interpolation points together with an early termination condition. The obtained results are comparable with the outcome of state-of-the-art rational interpolation techniques based on the ...
openaire +4 more sources
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
On the Singularity of Multivariate Hermite Interpolation of Total Degree
We study the singularity of multivariate Hermite interpolation of type total degree on m nodes with 3 ...
Zhongyong Hu +2 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source

