Results 31 to 40 of about 30,800 (259)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

A new multiplier for Lagrange interpolation in constrained non linear optimization [PDF]

open access: yesالمجلة العراقية للعلوم الاحصائية, 2010
In this paper, we have investigated a new multiplier for the Lagrange interpolation by modifying the initial value of the multiplier in order to reduce the errors and avoid the use of arbitrary values for the initial .
ABBAS Y. AL-BAYIATI   +2 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Gaussian Convolutions Numerical Approximations Based on Interpolation

open access: yes, 2001
Gaussian convolutions are perhaps the most often used image operators in low-level computer vision tasks. Surprisingly though, there are precious few articles that describe efficient and accurate implementations of these operators.In this paper we describe numerical approximations of Gaussian convolutions based on interpolation.
van den Boomgaard, R., van der Weij, R.
openaire   +3 more sources

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Numerical treatments for a multi-time delay complex order mathematical model of HIV/AIDS and malaria

open access: yesAlexandria Engineering Journal, 2022
In this artical, we present a novel complex order nonlinear mathematical model of HIV/AIDS and Malaria co-infection with multi-delay. The proposed model is formulated as a system of twelve complex order differential equations.
N.H. Sweilam   +2 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Another Six-Node Triangular Element for Structural Analysis

open access: yesEngineering Transactions, 2022
A six-node triangular element is presented in this paper for structural analysis. With this approach, the approximation functions of the interpolation strategy are given by using the double interpolation procedure, which includes nodal values as well as ...
Lan HOANG THAT TON
doaj   +1 more source

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