A Metal‐Free Carbon Monoxide Prodrug Suppresses Metastasis of Pancreatic and Breast Cancer
A metal‐free carbon monoxide (CO) prodrug, CO‐116, delivers controlled systemic CO without inhalation. CO suppresses the HRG1–heme axis, reducing intracellular heme availability. Attenuation of this pathway inhibits metastatic progression in pancreatic and triple‐negative breast cancer models.
Tiantian Zhang +15 more
wiley +1 more source
Efficient next-generation reservoir computing: An analog in-memory implementation using memristor crossbar arrays. [PDF]
Lin Z +5 more
europepmc +1 more source
Learnable Diffusion Framework for Mouse V1 Neural Decoding
We introduce Sensorium‐Viz, a diffusion‐based framework for reconstructing high‐fidelity visual stimuli from mouse primary visual cortex activity. By integrating a novel spatial embedding module with a Diffusion Transformer (DiT) and a synthetic‐response augmentation strategy, our model outperforms state‐of‐the‐art fMRI‐based baselines, enabling robust
Kaiwen Deng +2 more
wiley +1 more source
Data-driven discovery of digital twins in biomedical research. [PDF]
Métayer C, Ballesta A, Martinelli J.
europepmc +1 more source
An on‐demand ultra‐reconfigurable intelligent vision system with hierarchical reconfigurability from device to system levels is demonstrated. Through co‐design of a multi‐paradigm device, reconfigurable circuits, and adaptive system architecture/algorithms, the system enables seamless switching among spiking, non‐spiking, neuromorphic imaging (NI), and
Biyi Jiang +7 more
wiley +1 more source
Enhanced twin delayed DDPG with prioritized experience replay and Noisy Nets for regional economic dispatch. [PDF]
Xu C +5 more
europepmc +1 more source
A programmable 2048‐element circular ultrasound array combined with a compact acoustic lens produces a thin “sound sheet” over a large field of view, and records echoes with wide angular diversity across the ring aperture. Coherence‐enhanced beamforming converts full‐matrix data into high‐contrast tomographic slices, delivering near‐diffraction‐limited
Qiu‐De Zhang +11 more
wiley +1 more source
Computing Rate-Distortion Functions of Continuous Memoryless Sources via Discrete Algorithms: An Integrated Scheme with Convergence Guarantee and Algorithmic Acceleration. [PDF]
Chen L +5 more
europepmc +1 more source
The Origin of Efficiency in III‐Nitride Micro‐Light‐Emitting Diodes
The images show panchromatic cathodoluminescence of III‐V materials, which reveal that AlGaInP red wafers, having fewer defects, support longer carrier diffusion lengths. Meanwhile, the density of defects increases with longer emission wavelengths in the InGaN system, illustrating how generated carriers pass through the material and how defects limit ...
Jeong‐Hwan Park +11 more
wiley +1 more source
A fast, accurate and oscillation-free spectral collocation solver for high-dimensional transport problems. [PDF]
Cavallini N +3 more
europepmc +1 more source

