Results 41 to 50 of about 14,397 (244)

Analysis of typical programming mistakes made by first and second year IT students

Journal of Computer Sciences Institute, 2020
The research paper contains a review and analysis of common programming mistakes made by first and second year students of Computer Science. The data were collected during the courses entitled “Algorithmics and Data Structures” and “Numerical Methods ...
Monika Kaczorowska
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Mathematical model, numerical methods, additional experiments. from Optimizing adaptive cancer therapy: dynamic programming and evolutionary game theory

, 2020
Recent clinical trials have shown that adaptive drug therapies can be more efficient than a standard cancer treatment based on a continuous use of Maximum Tolerated Doses (MTD). The adaptive therapy paradigm is not based on a preset schedule; instead, the doses are administered based on the current state of tumour.
Gluzman, Mark, Scott, Jacob G., Vladimirsky, Alexander   +2 more
openaire   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Simulation of Physical, Chemical, and Biochemical Environmental Processes with Spreadsheets and VBA

Spreadsheets in Education, 2021
Dynamic simulation of physical, chemical, and biochemical reactions is usually difficult for environmental engineering students since most of water and wastewater treatment systems rely on several combinations of these reactions.
Selami Demir
doaj  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Levenberg-Marquardt Method for the Eigenvalue Complementarity Problem

The Scientific World Journal, 2014
The eigenvalue complementarity problem (EiCP) is a kind of very useful model, which is widely used in the study of many problems in mechanics, engineering, and economics.
Yuan-yuan Chen, Yan Gao
doaj   +1 more source

STUDENTS 'TRAINING OF THE PHYSICO-MATHEMATICAL PROFILE OF THE METHODS OF THE METHODS USING THE INTEGRATED ENVIRONMENT OF WORD AND MATLAB

Ìнформаційні технології в освіті, 2018
The article discusses the possibilities of using the integrated Word and Matlab environment for training students of the physics and mathematical profile of computing methods.
Doroshenko M.
doaj   +1 more source

Numerical Methods for Mathematical Programs with Disjunctive Constraints

, 2016
Motiviert durch steigendes Interesse an mathematischen Programmen mit komplementaren Nebenbedingungen (en. MPCCs) und mathematischen Programmen mit verschwindenden Nebenbedingungen (en. MPVCs) beschaftigen wir uns in dieser Arbeit mit einer Verallgemeinerung dieser Programme - sogenannte mathematische Programme mit disjunktiven Nebenbedingungen (en ...
openaire   +2 more sources