Results 131 to 140 of about 2,855,492 (322)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
A Validated Thermal Computational Fluid Dynamics Model of Wine Warming in a Glass
Oenophiles are aware that the temperature at the time of drinking can profoundly shape wine’s sensory attributes. Wine is usually served and drunk below room temperature but warms up after pouring due to heat exchange with warmer surroundings. This study
Maximilian Kannapinn +2 more
doaj +1 more source
Treatise on Analytic Nonlinear Optimal Guidance and Control Amplification of Strictly Analytic (Non-Numerical) Methods. [PDF]
Sands T.
europepmc +1 more source
Numerical investigation of splitter plate effect on bluff body using finite volume method
Azmil Afifi +2 more
openalex +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Numerical Methods in Studies of Liquid Crystal Elastomers. [PDF]
Soltani M +4 more
europepmc +1 more source
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Accuracy Evaluation of Thermoelastic Stress Analysis with the Use of Experimental and Numerical Methods. [PDF]
Misiewicz R, Moczko P, Bajcar A.
europepmc +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source

