Results 31 to 40 of about 10,882 (268)

NOVEL NUMERICAL PROCEDURES FOR LIMIT ANALYSIS OF STRUCTURES: MESH-FREE METHODS AND MATHEMATICAL PROGRAMMING [PDF]

open access: yes, 2010
Current research in the field of limit analysis is focussing on the development of numerical tools which are sufficiently efficient and robust to be used in engineering practice.
Le, Canh
core  

Feedback methods for inverse simulation of dynamic models for engineering systems applications [PDF]

open access: yes, 2011
Inverse simulation is a form of inverse modelling in which computer simulation methods are used to find the time histories of input variables that, for a given model, match a set of required output responses.
David J. Murray-Smith   +1 more
core   +1 more source

Optimization of the magnetostrictional molding composites structure [PDF]

open access: yesE3S Web of Conferences
The paper presents the methodology of multi-criteria synthesis of magnetostrictive cast composites with high physical-mechanical and anti-corrosive properties.
Bormotov Alelexei
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Estimation of Distribution Algorithms with Fuzzy Sampling for Stochastic Programming Problems

open access: yesApplied Sciences, 2020
Generating practical methods for simulation-based optimization has attracted a great deal of attention recently. In this paper, the estimation of distribution algorithms are used to solve nonlinear continuous optimization problems that contain noise. One
Abdel-Rahman Hedar   +2 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Modeling, Simulation, and Design of Self-Assembling Space Systems: Accurate Collision Detection, Robust Time Integration, and Optimal Control [PDF]

open access: yes, 2013
Motivated by issues inherent in modeling and designing self-assembling systems (e.g. multiple collisions, collisions between non-smooth bodies, clumping and jamming behaviors, etc.), the goal of this thesis is to develop robust numerical tools that ...
Gwendolyn B. Johnson   +1 more
core   +1 more source

Approaches to Numerical Solution of Optimal Control Problem Using Evolutionary Computations

open access: yesApplied Sciences, 2021
Two approaches to the numerical solution of the optimal control problem are studied. The direct approach is based on the reduction of the optimal control problem to a nonlinear programming problem.
Askhat Diveev   +2 more
doaj   +1 more source

Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane   +10 more
wiley   +1 more source

A decomposition procedure based on approximate newton directions [PDF]

open access: yes, 2001
The efficient solution of large-scale linear and nonlinear optimization problems may require exploiting any special structure in them in an efficient manner.
Conejo, Antonio J.   +3 more
core  

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