Results 31 to 40 of about 575,458 (263)

Numerical Simulation of Two Hailstorm Processes Based on CMA-MESO

应用气象学报
High-resolution numerical models coupled with detailed cloud microphysical schemes are essential tools for in-depth investigation of hail cloud structure and formation mechanisms.
Chen Xiaomin, Liu Qijun, Zou Qian, Liao Xiaoli, Zhang Yixuan   +4 more
doaj   +1 more source

Modelling Combined Intravenous Thrombolysis and Mechanical Thrombectomy in Acute Ischaemic Stroke: Understanding the Relationship between Stent Retriever Configuration and Clot Lysis Mechanisms

Life, 2021
Background: Combined intravenous thrombolysis and mechanical thrombectomy (IVT-MT) is a common treatment in acute ischaemic stroke, however the interaction between IVT and MT from a physiological standpoint is poorly understood.
Emily Louise Manchester, Dylan Roi, Boram Gu, Xiao Yun Xu, Kyriakos Lobotesis   +4 more
doaj   +1 more source

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar, Karen Thibaudeau, Mary Mathias, Heather McDaniel, Madlen Reschke, Klaus Tenbrock, Joseph M. Parker, Amy Shapiro   +7 more
wiley   +1 more source

Emission Control and Sensitivity Regime Shifts Drive the Decline in Extreme Ozone Concentration in the Sichuan Basin During 2015–2024

Remote Sensing
In recent years, ozone (O3) pollution has become a prominent air quality concern in the Sichuan Basin (SCB). Based on surface O3 measurements from 22 cities between 2015 and 2024, this study investigates the evolution of extreme O3 pollution events and ...
Hanqing Kang, Bojun Liu, Lei Hong, Jingchuan Shi, Hua Lu, Ying Zhang, Zhaobing Guo   +6 more
doaj   +1 more source

Numerical Simulation of Dynamic Response and Evaluation of Flexural Damage of RC Columns under Horizontal Impact Load

Applied Sciences, 2021
By using the ABAQUS finite element (FE) model, which has been verified by experiments, the deformation and internal force changes of RC columns during the impact process are investigated, and a parametric analysis is conducted under different impact ...
Bin Hu, Jian Cai, Jiabin Ye
doaj   +1 more source

Guidelines for Pediatric Radiotherapy Simulation: A Report From the Children's Oncology Group Radiation Oncology Discipline

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric radiation therapy presents unique challenges compared to adult treatments, including those of immobilization, potential need for sedation, and the critical importance of accurate, reproducible positioning. Additionally, heightened attention to imaging doses is necessary to minimize long‐term toxicity in survivors.
Parham Alaei, Stephen Mihalcik, Sujith Baliga, Young Kwok, Dana Casey, Eric Ehler, Christiane Burton, John C. Breneman, Daphne A. Haas‐Kogan, Suzanne L. Wolden, Arnold C. Paulino, Nadia N. Laack, Natia Esiashvili, Sarah Milgrom, Christine Hill‐Kayser, Thomas J. Fitzgerald, John A. Kalapurakal, Chia‐Ho Hua   +17 more
wiley   +1 more source

Vibration Measurement and Numerical Modeling Analysis of Transformer Windings and Iron Cores Based on Voltage and Current Harmonics

Machines, 2022
The operating condition and structural state of the converter transformer are closely related to vibration. Abundant harmonics aggravate the vibration of windings and iron cores, resulting in frequent mechanical structural failures, which seriously ...
Peiyu Jiang, Zhanlong Zhang, Zijian Dong, Yu Yang   +3 more
doaj   +1 more source

Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall, Emma N. Harrison, Genevieve C. Kendall   +2 more
wiley   +1 more source

Quantitative systems pharmacology model of B cell immune response in mouse

Frontiers in Immunology
B cell-mediated immunity plays a crucial role in long-term humoral protection. However, dysregulation of B cell development and differentiation may lead to the persistence of autoreactive clones, contributing to autoimmune diseases.
Yaroslav Ugolkov, Yaroslav Ugolkov, Yaroslav Ugolkov, Alina Volkova, Alina Volkova, Gabriel Helmlinger, Kirill Peskov, Kirill Peskov, Kirill Peskov, Victor Sokolov, Victor Sokolov   +10 more
doaj   +1 more source

The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo, Miriam A. Bornhorst, Angela J. Waanders, Sara Zarnegar‐Lumley, Ashwin Lakshman Koppayi, Lucy A. Godley   +5 more
wiley   +1 more source