Results 41 to 50 of about 42,341,612 (306)

An integrative mechanistic model of thymocyte dynamics

Frontiers in Immunology
BackgroundThe thymus plays a central role in shaping human immune function. A mechanistic, quantitative description of immune cell dynamics and thymic output under homeostatic conditions and various patho-physiological scenarios are of particular ...
Victoria Kulesh, Victoria Kulesh, Kirill Peskov, Kirill Peskov, Kirill Peskov, Kirill Peskov, Gabriel Helmlinger, Gennady Bocharov, Gennady Bocharov, Gennady Bocharov   +9 more
doaj   +1 more source

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine, Hallie Coltin, Sylvia Cheng, Lucie Lafay‐Cousin, Vanan Issai Magimairajan, Craig Erker, Stéphanie Vairy, Lynette Bowes, Adam Fleming, Donna Johnston, Sarah McKillop, Roona Sinha, Julie Bennett, Christina Coleman, Laura Wheaton, Shayna Zelcer, Samuele Renzi, Thai Hoa Tran   +17 more
wiley   +1 more source

Mathematical modeling of endogenous and exogenously administered T cell recirculation in mouse and its application to pharmacokinetic studies of cell therapies

Frontiers in Immunology
IntroductionIn vivo T cell migration has been of interest to scientists for the past 60 years. T cell kinetics are important in the understanding of the immune response to infectious agents.
Antonina Nikitich, Antonina Nikitich, Gabriel Helmlinger, Kirill Peskov, Kirill Peskov, Kirill Peskov, Kirill Peskov, Gennady Bocharov, Gennady Bocharov, Gennady Bocharov   +9 more
doaj   +1 more source

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

Numerical Simulation of Two Hailstorm Processes Based on CMA-MESO

应用气象学报
High-resolution numerical models coupled with detailed cloud microphysical schemes are essential tools for in-depth investigation of hail cloud structure and formation mechanisms.
Chen Xiaomin, Liu Qijun, Zou Qian, Liao Xiaoli, Zhang Yixuan   +4 more
doaj   +1 more source

Numerical Modeling of Flood Wave Behavior with Meandering Effects (Euphrates River, Haditha-Hit) [PDF]

Engineering and Technology Journal, 2011
A numerical model for routing of flood wave in a part of meandering river is presented. It is based on a modified form of the complete one-dimensional Saint- Venant equations of unsteady flow.
Muhanned J. Al-Kazwini, Rafa H. Al-Suhaily, Sadiq A. Al-hdawi   +2 more
doaj   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

Emission Control and Sensitivity Regime Shifts Drive the Decline in Extreme Ozone Concentration in the Sichuan Basin During 2015–2024

Remote Sensing
In recent years, ozone (O3) pollution has become a prominent air quality concern in the Sichuan Basin (SCB). Based on surface O3 measurements from 22 cities between 2015 and 2024, this study investigates the evolution of extreme O3 pollution events and ...
Hanqing Kang, Bojun Liu, Lei Hong, Jingchuan Shi, Hua Lu, Ying Zhang, Zhaobing Guo   +6 more
doaj   +1 more source

Efektivitas Krib Untuk Mengurangi Gerusan Di Tikungan Luar Sungai Bengawan Solo

Jurnal Teknik Hidraulik, 2019
Bengawan Solo River considered as a meander river. This condition has potentially triggered local scouring due to high flow velocity at the outer bend of the river.
James Zulfan, Yiniarti Eka Kumala
doaj   +1 more source

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source