Results 121 to 130 of about 347,675 (311)

Role of Strong Sea Surface Temperature Diurnal Variation in Triggering the Summer Monsoon Onset Over the Bay of Bengal in a Climate Model

open access: yesGeophysical Research Letters
The earliest Asian summer monsoon onset (SMO) occurs in the Bay of Bengal (BoB), heralding the coming of the rainy season. In late April or early May, the strong sea surface temperature (SST) diurnal variation accompanied by ocean surface warming ...
Yajuan Song   +4 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Critical evaluation of numerical techniques for highly non-linear field diffusion modelling [PDF]

open access: yes, 2010
Various numerical techniques have been applied to multidimensional field diffusion problems with front-type behaviour, moving boundaries and non-linear material properties.
Golosnoy, Igor O., Sykulski, Jan K.
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Wave spectrum Reconstruction Parameters for nested wave modeling in the China-adjacent seas from 2000 to 2024

open access: yesScientific Data
The storage and retrieval of wave spectra for boundary conditions in nested wave modeling are computationally intensive due to the substantial storage requirements of each spectrum.
Xingjie Jiang   +3 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Numerical Modeling of Pollutant Emissions with Detailed Kinetics: from Ideal Reactors to Flames [PDF]

open access: yes, 2013
IP3. This works aims to present the activity of the research group in modeling reacting systems with hundreds of species and thousands of reactions as those typical of combustion and of pollutant emission formation, in particular. Aliphatic species up to
CUOCI, ALBERTO   +3 more
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

International Conference for Mathematical Modeling and Optimization in Mechanics, 6-7 March, 2014, Jyväskylä, Finland : honor of the 70th anniversary of Prof. Nikolay Banichuk [PDF]

open access: yes, 2014
This book of abstracts presents materials of the International Conference for Mathematical Modeling and Optimization in Mechanics (MMOM 2014) 6-7 March 2014, Jyväskylä, Finland.
International Conference for Mathematical Modeling and Optimization in Mechanics
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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