Results 111 to 120 of about 900,805 (301)

Key aspects in 3D fatigue crack closure numerical modelling [PDF]

open access: yes, 2018
Since long time, fatigue crack closure has been studied by means of finite element models. Initially by bi-dimensional models and recently, due to the higher computational capabilities, the use of three-dimensional models has been extended, providing a
Camas, Daniel   +2 more
core  

An Approach for Accelerating Incompressible Turbulent Flow Simulations Based on Simultaneous Modelling of Multiple Ensembles

open access: yes, 2018
The present paper deals with the problem of improving the efficiency of large scale turbulent flow simulations. The high-fidelity methods for modelling turbulent flows become available for a wider range of applications thanks to the constant growth of ...
Krasnopolsky, Boris
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Distribution and trend of explosive cyclones over the Southern Ocean and associated atmospheric and oceanic changes during 1980–2020

open access: yesGeoscience Letters
In this study, we investigate the climatology and trend of explosive cyclones (ECs) over the Southern Ocean (50oS–70oS) during 1980–2020 by combining a method that is most suited for identifying and tracking cyclones in the Southern Ocean and a latest ...
Xiaoqi Xu   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Interannual connection of winter Barents-Kara sea-ice variability to ENSO regulated by Atlantic Multidecadal Oscillation

open access: yesEnvironmental Research Communications
In this study, the impact of Atlantic Multidecadal Oscillation (AMO) on the connection of winter sea-ice concentration (SIC) over Barents-Kara Seas (BKS) to El Niño-Southern Oscillation (ENSO) is explored.
Jiaqi Shi, Binhe Luo, Yao Yao, Dehai Luo
doaj   +1 more source

Biased Aerosol Wet Deposition CAM5 Simulations: A Result of Misrepresented Convective-Stratiform Precipitation Partitioning When Benchmarked Against SPCAM

open access: yesRemote Sensing
Wet deposition is a major sink for atmospheric aerosols, but its representation in conventional global climate models (GCMs) remains highly uncertain, partly as a result of the partitioning between convective and stratiform precipitation. Using the Super-
Wenwen Xia, Yujun He, Bin Wang
doaj   +1 more source

Advances in friction stir welding of steel : Project HILDA [PDF]

open access: yes, 2014
A microstructure and property evaluation of friction stir welded DH36 6mm plate has been undertaken. The study examined a wide range of process parameters and, from this, a process parameter envelope has been developed and an initial process parameter ...
Arbaoui, Larbi   +6 more
core  

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