Results 131 to 140 of about 175,188 (311)
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Finite element modelling of linear rolling contact problems
The present work is devoted to the finite element modelling of linear hyperbolic rolling contact problems. The main equations encountered in rolling contact mechanics are reviewed in the first part of the paper, with particular emphasis on applications ...
Axel Målqvist +3 more
core +1 more source
A review of numerical analysis of friction stir welding
, 2014 Friction stir welding is a relatively new solid-state joining technique which is widely adopted in different industry fields to join different metallic alloys that are hard to weld by conventional fusion welding. Friction stir welding is a highly complex
He, Xiaocong, Gu, Fengshou, Ball, Andrew
core +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Dynamics and Sensitivity of the Lifecycle of Hepatitis B Virus
PathogensA detailed mathematical model has been developed for the dynamics of hepatitis B virus (HBV) infection in a single cell. It provides a platform for a better quantitative understanding of the biochemical kinetics of the HBV lifecycle. The model is used to
Dmitry Grebennikov +7 more
doaj +1 more source
, 2001 Includes bibliography.Mine warfare is a very effective method of warfare as it has the element of surprise, it doesn't require interaction with the enemy, and it has a high percentage of fatalities. Because of this, mine warfare has been used extensively
Daykin, Leigh Milburn Atkinson
core
, 2014 This study presents a novel application of the Transmission Line Matrix Method (TLM) for the modelling of the dynamic behaviour of non-linear hybrid systems for CNC machine tool drives.
Longstaff, Andrew P. +9 more
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Game Theory-Based Risk Assessment of the Use of Autonomous Cars in an Urbanized Area
MathematicsWith the advancement of autonomous vehicles and their integration into urbanized areas, new challenges emerge related to safety and risk management. This paper presents an approach to assessing the risks of using autonomous cars in urban environments ...
Vasilena Adamova +4 more
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source