Results 141 to 150 of about 68,332 (263)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Influence of Novel "Umbrella"-Type Ladle Shroud on Liquid Steel Flow in a Two-Strand Slab Tundish: Physical and Numerical Modelling. [PDF]

Materials (Basel)
Cwudziński A, Fogaraš L, Demeter J, Demeter P, Buľko B.   +4 more
europepmc   +1 more source

Numerical Modelling of the Constitutive Behaviour of FRCM Composites through the Use of Truss Elements. [PDF]

Materials (Basel), 2023
Oddo MC, Minafó G, Di Leto M, La Mendola L.   +3 more
europepmc   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Experimental and numerical modelling of desiccation shrinkage process of kaolin clays. [PDF]

Sci Rep
Cheng W, Bian H, Shi H, Xun F.
europepmc   +1 more source

Numerical Modelling of the Mechanical Behaviour of Carbon and Non-Carbon Nanotubes and Their Complex Structures. [PDF]

Materials (Basel), 2022
Sakharova NA.
europepmc   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Snow avalanche susceptibility, hazard, and exposure assessment in the Western Himalaya using machine learning and numerical modelling. [PDF]

Sci Rep
Abhinav A, Sattar A.
europepmc   +1 more source

Contributions of deep learning to automated numerical modelling of the interaction of electric fields and cartilage tissue based on 3D images. [PDF]

Front Bioeng Biotechnol, 2023
Che VL, Zimmermann J, Zhou Y, Lu XL, van Rienen U.   +4 more
europepmc   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source