Results 161 to 170 of about 891,924 (295)

Reconstructing subsurface fracture geometries in rock slope instabilities through ambient vibration-based numerical modelling inversion. [PDF]

Sci Rep
Grechi G, Moore JR, D'Amico S, Martino S.   +3 more
europepmc   +1 more source

Experimental Research and Numerical Modelling of the Cold Forming Process of the Inconel 625 Alloy Sheets Using Flexible Punch. [PDF]

Materials (Basel), 2023
Balcerzak M, Żaba K, Hojny M, Puchlerska S, Kuczek Ł, Trzepieciński T, Novák V.   +6 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Nonlinear Behaviour of Aluminium and Passive Brackets in Ventilated Facades: Experimental Tests and Numerical Modelling. [PDF]

Materials (Basel)
Zawiślak Ł, Schabowicz K, Kopyłow O.
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

An integrated numerical modelling framework for simulation of the multiphysics in sonoprocessing of materials. [PDF]

Ultrason Sonochem
Qin L, Xiang K, Li L, Tzanakis I, Eskin D, Mi J.   +5 more
europepmc   +1 more source

The Significance of Cross-Sectional Shape Accuracy and Non-Linear Elasticity on the Numerical Modelling of Cerebral Veins under Tensile Loading. [PDF]

Biology (Basel), 2023
Fernandes FAO, Silveira CIC.
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Integration of InSAR and numerical modelling to assess tailings pond slope deformation affected by reservoir water. [PDF]

Sci Rep
Lu L, Li M, Chao L.
europepmc   +1 more source

A Numerical Modelling Framework for Investigating the Ballistic Performance of Bio-Inspired Body Armours. [PDF]

Biomimetics (Basel), 2023
Ghazlan A, Ngo T, Tan P, Tran P, Xie YM.
europepmc   +1 more source