Results 91 to 100 of about 376,453 (199)

2D and 3D numerical models to evaluate trabecular bone damage. [PDF]

Med Biol Eng Comput, 2021
Buccino F, Colombo C, Duarte DHL, Rinaudo L, Ulivieri FM, Vergani LM.   +5 more
europepmc   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Numerical Models of the Connection of Thin-Walled Z-Profile Roof Purlins. [PDF]

Materials (Basel), 2021
Pařenica P, Lehner P, Brožovský J, Krejsa M.   +3 more
europepmc   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Response and input time history dataset and numerical models for a miniaturized 3D shear frame under damaged and undamaged conditions. [PDF]

Data Brief, 2022
Hoda MA, Kuncham E, Sen S.
europepmc   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

System Reliability Analysis of Concrete Arch Dams Considering Foundation Rock Wedges Movement: A Discussion on the Limit Equilibrium Method

Infrastructures
In this paper, a discussion on the applicability and limitations of the limit equilibrium method is presented. In this manner, the reliability of a concrete arch dam-foundation system under static loading is evaluated by considering a set of potentially ...
Narjes Soltani, Ignacio Escuder-Bueno, Mateja Klun   +2 more
doaj   +1 more source

Numerical Models Can Assist Choice of an Aortic Phantom for In Vitro Testing. [PDF]

Bioengineering (Basel), 2021
Comunale G, Di Micco L, Boso DP, Susin FM, Peruzzo P.   +4 more
europepmc   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Analytical and Numerical Models of Thermoplastics: A Review Aimed to Pellet Extrusion-Based Additive Manufacturing. [PDF]

Polymers (Basel), 2021
Pricci A, de Tullio MD, Percoco G.
europepmc   +1 more source