Results 71 to 80 of about 376,453 (199)
Study of Complexity of Numerical Models of a Strengthened Timber Beam. [PDF]
Szczecina M.
europepmc +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Finite Element Analysis of Electromagnetic Forming Process Applied on Thin Wall Metallic Workpieces [PDF]
The paper deals with numerical simulationsof magnetoforming process applied on thin wallmetallic workpieces. Finite element models aredeveloped using ANSYS Multiphysics as a support.The transient electromagnetic field phenomena aresequentially coupled ...
Sorin Pasca +2 more
doaj
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Computer Insight into the Molecular Level of Heart Failure. What is the Role of NCX?
Though congestive heart failure is a leading cause of death in our population, the pathophysiological mechanisms at molecular level remain to be elucidated. This paper discusses the contribution of NCX to the pathological pattern of intracellular calcium
M. Fischer +3 more
doaj
The last decades continuously increasing of the economical activities in the coastal environment of the Black Sea is obviously leading to the enhancement of the pollution risks due to accidental oil spillages.
Liliana Rusu
doaj +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
A novel green lubricating oil additive (carbon quantum dot (CQD) particle-doped nickel (Ni-CQD)) was synthesized from citric acid and nickel acetate. The effects of CQD and Ni-CQD nanoparticles on the tribological behaviors of polyethylene glycol (PEG200)
Zhiqiang Tu +8 more
doaj +1 more source
Characteristics of Earthquake Cycles: A Cross-Dimensional Comparison of 0D to 3D Numerical Models. [PDF]
Li M, Pranger C, van Dinther Y.
europepmc +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source

