Results 31 to 40 of about 4,199 (203)

Quantifying the impact of precision errors on quantum approximate optimization algorithms

Physical Review Research
The quantum approximate optimization algorithm (QAOA) is a hybrid quantum-classical algorithm that seeks to achieve approximate solutions to optimization problems by iteratively alternating between intervals of controlled quantum evolution.
Gregory Quiroz, Paraj Titum, Phillip Lotshaw, Pavel Lougovski, Kevin Schultz, Eugene Dumitrescu, Itay Hen   +6 more
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

A Four‐Dimensional Variational Constrained Neural Network‐Based Data Assimilation Method

Journal of Advances in Modeling Earth Systems
Advances in data assimilation (DA) methods and the increasing amount of observations have continuously improved the accuracy of initial fields in numerical weather prediction during the last decades. Meanwhile, in order to effectively utilize the rapidly
Wuxin Wang, Kaijun Ren, Boheng Duan, Junxing Zhu, Xiaoyong Li, Weicheng Ni, Jingze Lu, Taikang Yuan   +7 more
doaj   +1 more source

Qualitative properties of solutions to generalized eigenvalue problems [PDF]

Arab Journal of Mathematical Sciences
PurposeThis paper investigates the qualitative properties of solutions to a fractional (p,)-Laplace eigenvalue problem with nonhomogeneous terms.
Abdelhamid Gouasmia, Oumaima Ouennas, Amel Bekhouche   +2 more
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Reinforcement Learning in Different Phases of Quantum Control

Physical Review X, 2018
The ability to prepare a physical system in a desired quantum state is central to many areas of physics such as nuclear magnetic resonance, cold atoms, and quantum computing.
Marin Bukov, Alexandre G. R. Day, Dries Sels, Phillip Weinberg, Anatoli Polkovnikov, Pankaj Mehta   +5 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Effective Alternating Direction Optimization Methods for Sparsity-Constrained Blind Image Deblurring

Sensors, 2017
Single-image blind deblurring for imaging sensors in the Internet of Things (IoT) is a challenging ill-conditioned inverse problem, which requires regularization techniques to stabilize the image restoration process.
Naixue Xiong, Ryan Wen Liu, Maohan Liang, Di Wu, Zhao Liu, Huisi Wu   +5 more
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source