Results 81 to 90 of about 12,580 (256)
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
FEBS Open Bio, EarlyView.Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
Numerical modelling of heat transfer in a tube furnace for steel wire annealing [PDF]
, 2012 In order to relieve stresses from cold drawing and to regain ductility, steel wires are annealed in furnaces under prolonged exposure to an appropriate temperature termed as ‘soaking’.
Perera, Noel +3 more
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Convective Flux Analysis on the Instability of One-Dimensional Detonation
AerospaceOne-dimensional numerical simulations using the Euler equations and irreversible one-step Arrhenius kinetics are conducted to study the instability mechanism of a one-dimensional gaseous detonation.
Yunfeng Liu
doaj +1 more source
Adenosine triphosphate as a modulator of protein interactions and stability
FEBS Open Bio, EarlyView.ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
Natural quenching of stellar formation [PDF]
, 2018 Treballs Finals de Grau de Física, Facultat de Física, Universitat de Barcelona, Curs: 2018, Tutor: Eduard Salvador SoléObservation shows that, over cosmic history, star formation increased until z = 2. After that it su ered a strong quenching.
Alfaro Rudilla, Víctor
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau +11 more
wiley +1 more source
Large Forgings: Microstructural Evolution and Residual Stresses Due to Quenching Treatments—A Combined Numerical and Experimental Approach [PDF]
, 2014 Based on numerical and experimental data, an FEM model was implemented to simulate quench treatments on large forging components. After experimental validation of convection coefficient laws between water and component surface, time–temperature curves ...
GUAGLIANO, MARIO +4 more
core +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Advanced Biology, Volume 9, Issue 3, March 2025.Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
Numerical methods and time-dependent physical models for the design and diagnostic of pulsed-dc magnetrons [PDF]
, 2006 Pulsed DC operation of magnetrons is a relatively new sputtering technique that significantly improves the properties of deposited layers. The understanding and control of phenomena taking place during pulsed DC sputtering requires new time-resolved ...
Moiseev, Tamara
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