Results 61 to 70 of about 72,811 (257)

An Efficient Fluid-Dynamic Analysis to Improve Industrial Quenching Systems

Metals, 2017
This paper addresses the problem of understanding the relationship between fluid flow and heat transfer in industrial quenching systems. It also presents an efficient analysis to design or optimize long standing quenching tanks to increase productivity ...
Manuel de J. Barrena-Rodríguez, Marco A. González-Melo, Francisco A. Acosta-González, Eddy Alfaro-López, Francisco A. García-Pastor   +4 more
doaj   +1 more source

Flame Enhancement and Quenching in Fluid Flows [PDF]

, 2002
We perform direct numerical simulations (DNS) of an advected scalar field which diffuses and reacts according to a nonlinear reaction law. The objective is to study how the bulk burning rate of the reaction is affected by an imposed flow.
Abel M, Abel M, Alexander Kiselev, Audoly B, Avellaneda M, Berestycki H, Bradley D, Chandrasekhar S, Drazin P G, Fife P C, Kanel Ya, Kolmogorov A N, Leonid Ryzhik, Natalia Vladimirova, Oleg Ruchayskiy, Pelcé P, Peter Constantin, Ronney P D, Taylor G I, Vladimirova N, Volpert A, Williams F A, Zeldovich Ya B   +22 more
core   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Temporal Interferometry: A Mechanism for Controlling Qubit Transitions During Twisted Rapid Passage with Possible Application to Quantum Computing [PDF]

, 2002
In an adiabatic rapid passage experiment, the Bloch vector of a two-level system (qubit) is inverted by slowly inverting an external field to which it is coupled, and along which it is initially aligned.
A. Barenco, A. Joye, A. Joye, A. M. Steane, A. R. Calderbank, C. Zener, D. Gottesman, D. P. DiVincenzo, E. Knill, Frank Gaitan, J. Preskill, J. W. Zwanziger, J. W. Zwanziger, K.-A. Suominen, K.-A. Suominen, K.-A. Suominen, L. Landau, M. V. Berry, N. A. Gershenfeld, P. W. Shor, R. Lim, W. R. Thorson   +21 more
core   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Method of lines and finite difference schemes with the exact spectrum for solution the hyperbolic heat conduction equation

Mathematical Modelling and Analysis, 2011
This paper is concerning with the 1-D initial–boundary value problem for the hyperbolic heat conduction equation. Numerical solutions are obtained using two discretizations methods – the finite difference scheme (FDS) and the difference scheme with the ...
Harijs Kalis, Andris Buikis
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Black Hole Growth, Baryon Lifting, Star Formation, and IllustrisTNG

The Astrophysical Journal, 2023
Quenching of star formation in the central galaxies of cosmological halos is thought to result from energy released as gas accretes onto a supermassive black hole.
G. Mark Voit, Benjamin D. Oppenheimer, Eric F. Bell, Bryan Terrazas, Megan Donahue   +4 more
doaj   +1 more source

Oscillation quenching in third order Phase Locked Loop coupled by mean field diffusive coupling

, 2016
We explore analytically the oscillation quenching phenomena (amplitude death and oscillation death) in a coupled third order phase locked loop (PLL) both in periodic and chaotic mode.
Chakraborty, S, Dandapathak, M, Sarkar, B C   +2 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source