Results 141 to 150 of about 3,494,748 (301)

An Improved Numerical Scheme for 2D Nonlinear Time-Dependent Partial Integro-Differential Equations with Multi-Term Fractional Integral Items

open access: yes
This paper is dedicated to investigating a highly accurate numerical solution for a class of 2D nonlinear time-dependent partial integro-differential equations with multi-term fractional integral items. These integrals are weakly singular with respect to
Yanying Ma, Fan Ouyang, Hongyan Liu
core   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

New Simplified High-Order Schemes for Solving SDEs with Markovian Switching Driven by Pure Jumps

open access: yesAxioms
New high-order weak schemes are proposed and simplified to solve stochastic differential equations with Markovian switching driven by pure jumps (PJ-SDEwMs).
Yang Li   +3 more
doaj   +1 more source

Three-Dimensional Waves Generated by a Running Pressure Disturbance : Numerical Computation by IAF Scheme

open access: yes, 1993
This paper deals with numerical computational method on three-dimensional surface waves which are generated by a running pressure disturbance. The computational method by modified IAF scheme is investigated.
塩谷, 茂明, 仲渡, 道夫
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Mathematical Analysis of Malware Spread in Digital Systems Using Atangana–Baleanu–Caputo Fractional Dynamics

open access: yesAlgorithms
This study explores the spread of malware within a digital framework by introducing a unique fractional-order model that employs the Atangana–Baleanu–Caputo (ABC) derivative.
Tharmalingam Gunasekar   +4 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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