Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
A tension spline fitted numerical scheme for singularly perturbed reaction-diffusion problem with negative shift. [PDF]
Ejere AH +3 more
europepmc +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
A new explicit numerical scheme for enhancement of heat transfer in Sakiadis flow of micro polar fluid using electric field. [PDF]
Nawaz Y +4 more
europepmc +1 more source
On the construction of boundary preserving numerical schemes [PDF]
Abstract Our aim in this note is to extend the semi-discrete technique by combine it with the split step method. We apply our new method to the Ait-Sahalia model and propose an explicit and positivity preserving numerical scheme.
openaire +3 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
An efficient numerical scheme for fractional host–parasite hyperparasite interaction model
In this paper, we analyse the unique characteristics of hyperparasites and discharge incidents in the initial stage of parasite populations. If hyperparasites are effectively developed in a population, they can play a crucial role in controlling host ...
Parveen Kumar +3 more
doaj +1 more source
An Efficient Numerical Scheme for Solving a Fractional-Order System of Delay Differential Equations. [PDF]
Kumar M.
europepmc +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
New Simplified High-Order Schemes for Solving SDEs with Markovian Switching Driven by Pure Jumps
New high-order weak schemes are proposed and simplified to solve stochastic differential equations with Markovian switching driven by pure jumps (PJ-SDEwMs).
Yang Li +3 more
doaj +1 more source

