A numerical scheme using multi-shockpeakons to compute solutions of the Degasperis-Procesi equation
Electronic Journal of Differential Equations, 2007 We consider a numerical scheme for entropy weak solutions of the DP (Degasperis-Procesi) equation $u_t - u_{xxt} + 4uu_x = 3u_{x}u_{xx}+ uu_{xxx}$. Multi-shockpeakons, functions of the form $$ u(x,t) =sum_{i=1}^n(m_i(t) -hbox{sign}(x-x_i(t))s_i(t ...
Hakon A. Hoel
doaj
A Two-Step High-Order Compact Corrected WENO Scheme
AlgorithmsIn this study, we introduce a novel 2-step compact scheme-based high-order correction method for computational fluid dynamics (CFD). Unlike traditional single-formula-based schemes, our proposed approach refines flux function values by leveraging results
Yong Yang +3 more
doaj +1 more source
Accurate numerical scheme for singularly perturbed parabolic delay differential equation. [PDF]
BMC Res Notes, 2021 Woldaregay MM, Duressa GF.
europepmc +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Production and dispersion of free radicals from transient cavitation Bubbles: An integrated numerical scheme and applications. [PDF]
Ultrason Sonochem, 2022 Peng K, Qin FGF, Jiang R, Qu W, Wang Q.
europepmc +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source