Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Optimization of refueling docking trajectory for multi-UAV formation
Aiming at the optimization of autonomous docking trajectory of unmanned receiver in the in-flight refueling, a high-precision computational fluid dynamics method was used to calculate the dangerous area behind the refueling aircraft as the obstacle in ...
WANG Yuyan +4 more
doaj +1 more source
Numerical validation of the incremental launching method of a steel bridge through a small-scale experimental study [PDF]
The final publication is available at Springer via http://dx.doi.org/10.1007/s40799-016-0037-5This article presents an experimental and a numerical study of an incremental launching process of a steel bridge.
Chacón Flores, Rolando Antonio +2 more
core +2 more sources
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
A note on hyperbolic relaxation of the Navier-Stokes-Cahn-Hilliard system for incompressible two-phase flows [PDF]
We consider the two-phase dynamics of two incompressible and immiscible fluids. As a mathematical model we rely on the Navier-Stokes-Cahn-Hilliard system that belongs to the class of diffuse-interface models.
Keim Jens +2 more
doaj +1 more source
Investigation of hidden-charm pentaquarks with strangeness $$S=-1$$ S = - 1
Recently, a new hidden-charm pentaquark state $$P_{cs}(4459)$$ P cs ( 4459 ) was reported by the LHCb Collaboration. Stimulated by the fact that all hidden-charm pentaquark states in $$S=0$$ S = 0 systems were successfully studied by the chiral quark ...
Xiaohuang Hu, Jialun Ping
doaj +1 more source
Simulation of Impedance Discontinuities Resulting from Degradation of Interconnections on Printed Circuit Boards [PDF]
Numerical simulation of impedance discontinuities resulting from degradation of interconnections on printed circuit ...
Dipartimento Di Elettronica +7 more
core +2 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Canopy height model and NAIP imagery pairs across CONUS
Canopy height models (CHM) provide detailed environmental vertical structure information and are an important indicator and input for ecological and geospatial applications.
Brady W. Allred +2 more
doaj +1 more source
The characteristics of shock wave loads from air blast near the water surface
Blasts near the water surface are one of the major threats to ships. Experiments were carried out to study the load characteristics of the shock wave on the water surface with TNT/RDX(40/60) explosives.
Chao HUANG +5 more
doaj +1 more source

