Results 71 to 80 of about 202,718 (259)

Searching for Critical Conditions During Lifeboat Launching – Simulations

open access: yesPolish Maritime Research, 2017
The article describes numerical simulations of the process of lifeboat launching at the ship’s side. The research aimed at finding the values of ship motion parameters which appear to be most dangerous for people in the lowered lifeboat due to the ...
Dymarski Czesław   +2 more
doaj   +1 more source

Lifetimes of Rogue Wave Events in Direct Numerical Simulations of Deep-Water Irregular Sea Waves

open access: yesFluids, 2019
The issue of rogue wave lifetimes is addressed in this study, which helps to detail the general picture of this dangerous oceanic phenomenon. The direct numerical simulations of irregular wave ensembles are performed to obtain the complete accurate data ...
Anna Kokorina, Alexey Slunyaev
doaj   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Numerical simulations of pipeline bending tests [PDF]

open access: yesApplied and Computational Mechanics, 2008
The paper compares numerical solution with results of experimental solution of pipeline under cyclic loading in elastoplastic domain. The pipeline was subjected to internal pressure and bending moment.
Halama R., Rojíček J.
doaj  

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Frequency as the Greenest Additive for Metal Plating: Mathematical and Experimental Study of Forcing Voltage Effects on Electrochemical Growth Dynamics

open access: yesInternational Journal of Electrochemical Science, 2011
Metal plating is a well-assessed and widespread technology. Though being a mature process (Ag plating is in fact the first known application of Volta’s battery in 1801, Al electrolysis was used to fabricate Napoleon III’s tableware for very special ...
Benedetto Bozzini   +2 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

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