Results 51 to 60 of about 1,442,504 (288)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Numerical Research of Flue Gas Denitrification Using the SNCR Method in an OP 650 Boiler

Energies, 2022
The presence of Poland in the European Union obliges the domestic economy and the professional energy sector to improve the condition of the natural environment by reducing the emissions of harmful substances into the environment.
Bartłomiej Hernik
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Numerical Simulations of Large Martian Impact Ripples

Geosciences, 2022
Ripples made from unimodal fine sands can grow much larger on Mars than on Earth, reaching wavelengths of 1–3 m and heights exceeding 1 dm. Smaller decimeter-wavelength ripples can be superimposed on them.
Hezi Yizhaq, Jasper F. Kok, Simone Silvestro, Lior Saban, Itzhak Katra   +4 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Numerical Simulations of Shock Wave-Driven Jets [PDF]

, 2007
We present the results of numerical simulations of shock wave-driven jets in the solar atmosphere. The dependence of observable quantities like maximum velocity and deceleration on parameters such as the period and amplitude of initial disturbances and ...
Arnaud M., B. De Pontieu, Beckers J. M., Bel N., Grossmann-Doerth U., L. Heggland, Tsiropoula G., V. H. Hansteen   +7 more
core   +2 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Turbulent particle pair diffusion: Numerical simulations.

PLoS ONE, 2019
A theory for turbulent particle pair diffusion in the inertial subrange [Malik NA, PLoS ONE 13(10):e0202940 (2018)] is investigated numerically using a Lagrangian diffusion model, Kinematic Simulations [Kraichnan RH, Phys.
Nadeem A Malik
doaj   +1 more source

Numerical Simulations of Pulverized Coal Combustion

KONA Powder and Particle Journal, 2014
Coal is an important energy resource for meeting the further demand for electricity, as coal reserves are much more abundant than those of other fossil fuels.
Ryoichi Kurose, Hiroaki Watanabe, Hisao Makino   +2 more
doaj   +1 more source

Numerical Simulations of Indian Ocean Tsunami by Tuna-m2 [PDF]

, 2006
The Sumatra-Andaman earthquake of magnitude 9.3 on the Richter scale occurred on 26 December 2004. It triggered off a series of tsunami waves that caused tremendous damage to the properties and lives along the affected coastal areas.
Loon, C. K. (Cham)
core