Results 61 to 70 of about 45,162 (207)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Searching for Critical Conditions During Lifeboat Launching – Simulations

open access: yesPolish Maritime Research, 2017
The article describes numerical simulations of the process of lifeboat launching at the ship’s side. The research aimed at finding the values of ship motion parameters which appear to be most dangerous for people in the lowered lifeboat due to the ...
Dymarski Czesław   +2 more
doaj   +1 more source

Numerical Simulations in Micromagnetism

open access: yes, 2017
Ao nível quântico, os materiais ferromagnéticos são caracterizados por magnetismo resultante do spin dos eletrões cuja descrição completa requer a aplicação da Mecânica Quântica. Estes materiais quando T
openaire   +2 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

3D Numerical Simulations of Magnetar Crustquakes

open access: yesThe Astrophysical Journal
Crustquakes are frequently invoked as a mechanism to trigger sudden transients in the magnetospheres of magnetars. In this picture, a mechanical failure of the crust excites seismic motions of the magnetar surface that launch force-free waves into the ...
Yuanhong Qu, Ashley Bransgrove
doaj   +1 more source

Numerical simulations of pipeline bending tests [PDF]

open access: yesApplied and Computational Mechanics, 2008
The paper compares numerical solution with results of experimental solution of pipeline under cyclic loading in elastoplastic domain. The pipeline was subjected to internal pressure and bending moment.
Halama R., Rojíček J.
doaj  

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Global dynamical properties of two discrete-time exponential systems

open access: yesJournal of Taibah University for Science, 2019
We explore the global dynamics of following three directional discrete-time exponential systems of difference equations: \[{x_{n + 1}} = \frac{{{\alpha _{19}} + {\beta _{19 }}{e^{ - {y_n}}}}}{{{\gamma _{19}} + {z_{n - 1}}}},\,\quad {y_{n + 1}} = \frac{{{\
A. Q. Khan
doaj   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

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