Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Elsner L, Mehrmann V. Convergence of block iterative methods for linear systems arising in the numerical solution of Euler equations. Numerische Mathematik.
Mehrmann, Volker, Elsner, Ludwig
core +1 more source
Numerical Solution of the Electric Field and Dielectrophoresis Force of Electrostatic Traveling Wave System. [PDF]
Yu Y +5 more
europepmc +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Analytical and Numerical Solution of a Poisson RBC model [PDF]
This paper analyses a RBC model in continuous time featuring deterministic incremental development of technology and stochastic fundamental inventions arriving according to a Poisson process.
Schlegel, Christoph
core
Orthogonal cubic splines for the numerical solution of nonlinear parabolic partial differential equations. [PDF]
Alavi J, Aminikhah H.
europepmc +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Renormalized charge and dielectric effects in colloidal interactions: a numerical solution of the nonlinear Poisson-Boltzmann equation for unknown boundary conditions. [PDF]
Schlaich A +4 more
europepmc +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Numerical solution of neutral delay differential equations using orthogonal neural network. [PDF]
Vinodbhai CD, Dubey S.
europepmc +1 more source

