This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Numerical solution of COVID-19 pandemic model via finite difference and meshless techniques. [PDF]
Zarin R +3 more
europepmc +1 more source
Theory of storage and retrieval of intense-broadband pulses at room temperature: analytical and numerical solutions [PDF]
Rodrigo Gutiérrez–Cuevas
openalex +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Exact and Numerical Solution of the Fractional Sturm-Liouville Problem with Neumann Boundary Conditions. [PDF]
Klimek M, Ciesielski M, Blaszczyk T.
europepmc +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Morphology of Ionic Micelles as Studied by Numerical Solution of the Poisson Equation. [PDF]
Zueva OS, Rukhlov VS, Zuev YF.
europepmc +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Numerical solution of the Burgers equation associated with the phenomena of longitudinal dispersion depending on time. [PDF]
Yonti Madie C, Kamga Togue F, Woafo P.
europepmc +1 more source
Energy conservation issues in the numerical solution of the semilinear wave equation [PDF]
Luigi Brugnano +2 more
openalex +1 more source

