Results 141 to 150 of about 2,129,625 (339)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

An Adaptive Method for the Numerical Solution of a 2D Monge-Ampère Equation [PDF]

open access: gold, 2021
Alexandre Caboussat   +2 more
openalex   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Modeling of bioaerosol transport in lower atmosphere layer with account of temperature and humidity heterogeneity

open access: yesУчёные записки Казанского университета: Серия Естественные науки, 2018
The paper describes a two-dimensional model of bioaerosol transport from a non-stationary source of admixture in the atmospheric boundary layer at the local level (the linear sizes of the studied area up to 40–50 km) taking into account the roughness and
K.G. Shvarts   +4 more
doaj  

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