Results 61 to 70 of about 190,411 (265)

The Impact of Velocity Update Frequency on Time Accuracy for Mantle Convection Particle Methods

open access: yesGeochemistry, Geophysics, Geosystems
Computing the velocity field is an expensive process for mantle convection codes. This has implications for particle methods used to model the advection of quantities such as temperature or composition.
S. J. Trim, S. L. Butler, R. J. Spiteri
doaj   +1 more source

Dynamics and Sensitivity of the Lifecycle of Hepatitis B Virus

open access: yesPathogens
A detailed mathematical model has been developed for the dynamics of hepatitis B virus (HBV) infection in a single cell. It provides a platform for a better quantitative understanding of the biochemical kinetics of the HBV lifecycle. The model is used to
Dmitry Grebennikov   +7 more
doaj   +1 more source

Numerical Stability in Complex Summation

open access: yesپژوهش‌های ریاضی, 2021
The natural and practical condition numbers for summation of complex numbers are introduced. These numbers measure the effect of loss of significant digits on the round-off error when computing a sum in floating point arithmetic. The relationship between
Hassan Majidian   +2 more
doaj  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Numerical Analysis of a High-Order Scheme for Space-Time Fractional Diffusion-Wave Equations with Riesz Derivatives

open access: yesMathematics
In this paper, we study a class of time–space fractional partial differential equations involving Caputo time-fractional derivatives and Riesz space-fractional derivatives. A computational scheme is developed by combining a discrete approximation for the
Anant Pratap Singh   +2 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

On the Aitken–Hotelling–Duncan Formula: Brief History, Direct Derivations, and Effective Conditioning

open access: yesMathematics
In the first part of this paper, we examine historical documents related to the well-known Sherman–Morrison–Woodbury (SMW) formula and suggest that Aitken–Hotelling–Duncan (AHD) is an appropriate name for the same formula.
Yunkai Zhou
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

FPU-Supported Running Error Analysis

open access: yesActa Polytechnica, 2010
A-posteriori forward rounding error analyses tend to give sharper error estimates than a-priori ones, as they use actual data quantities. One of such a-posteriori analysis – running error analysis – uses expressions consisting of two parts; one generates
T. Zahradnický, R. Lórencz
doaj  

A Sequential Approach to Numerical Simulations of Solidification with Domain and Time Decomposition

open access: yesApplied Sciences, 2019
Progress in computational methods has been stimulated by the widespread availability of cheap computational power leading to the improved precision and efficiency of simulation software.
Elzbieta Gawronska
doaj   +1 more source

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