Results 111 to 120 of about 1,526,252 (287)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Stress among nursing undergraduate students of a Brazilian public university

open access: yesInvestigación y Educación en Enfermería, 2016
Objective. To determine the level of stress among students of an undergraduate course in nursing of a Brazilian public university. Methods. Cross-sectional study involving 111 students who responded to the 30 item questionnaire of Costa and Polak for ...
Verusca Soares de Souza   +6 more
doaj  

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Promoting Change from ‘Child Protection’ to ‘Child and Family Welfare’: The Problems of the English System [PDF]

open access: yes, 2002
In England, the system for children and families in need of state intervention has developed in response to a series of political changes and to high profile and highly publicised child welfare ‘cases’.
Hetherington, Rachael, Nurse, Tracey
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Nurses\u27 Alumnae Association Bulletin - Volume 2 Number 4 [PDF]

open access: yes, 1943
Jefferson Marches On Remember!! Alumnae Day!! It\u27s Here Student Nurse Activities Red Cross Student Reserve Promotion Bits of Chatter from Base Unit #38 Promotion Congratulated by Phone Civilian Defense The Blue Book Attention The Graduate Nurses\u27 ...
Riland, Martha E
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Development and Effectiveness of Central Line-Associated Bloodstream Infection Management Education Program for Neonatal Intensive Care Unit Nurses

open access: yesNursing and Healthcare Science
Purpose: One or two sentences of background would be helpful to understand the problem. We developed and tested effectiveness of central line-associated bloodstream infection (CLABSI) management for neonatal intensive care unit (NICU) nurses.
Shinhye Chae, Hyoryung Shim, Hyejin Kim
doaj   +1 more source

Are Rural and Urban Newly Licensed Nurses Different? A Longitudinal Study of a Nurse Residency Programme [PDF]

open access: yes, 2014
Aim This study aimed to compare rural and urban nurse residency programme participants’ personal and job characteristics and perceptions of decision-making, job satisfaction, job stress, nursing performance and organisational commitment over time ...
Baernholdt, Marianne   +2 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

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