Results 41 to 50 of about 477,700 (249)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Care models for people with chronic diseases: integrative review

open access: yesInvestigación y Educación en Enfermería, 2017
Objective. To identify the care models and the impact of the use of these in the care of people with chronic diseases reported in the literature in the years 2000 to 2014. Methods.
Elis Martins Ulbrich   +4 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Insights gained through exploring UK midwifery care by US midwifery graduate students in a short-term study abroad: A qualitative study

open access: yesEuropean Journal of Midwifery
Introduction Student midwives exposed to effective systems of midwifery care in other countries can consider how aspects of this knowledge can translate into their healthcare system to improve maternal and infant perinatal outcomes.
Cindy L. Farley   +2 more
doaj   +1 more source

Validation of the Work Limitations Questionnaire in Brazilian Army military personnel

open access: yesInvestigación y Educación en Enfermería, 2018
Objective To validate the Work Limitations Questionnaire (WLQ) to measure presenteeism in Brazilian military personnel. Methods This is a test validation study conducted with 125 individuals of a military staff attending a Brazilian Army Unit.
Juliane Umann   +4 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Factors in the Transition from Legal to Illicit Drug Use in Young Adults from Northern Mexico

open access: yesInvestigación y Educación en Enfermería, 2019
Objective. This research sought to analyze the predictive effect of personal (personality traits), social (social support and social stigma) and community factors (characteristic of the neighborhood and exposure to consumption) on the transition of drug ...
Mayra Selene Ozuna Esprinosa   +4 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Human Security and Existential Threats: A Governance Framework for Planet, Peace, People & Prosperity

open access: yesCadmus, 2023
A key priority for Human Security in the 21st Century is the prevention of existential threats to human civilisation to ensure the well-being of our future generations.
Joanna Nurse
doaj  

Cooperative Learning and Hand Disinfection in Nursing Students

open access: yesInvestigación y Educación en Enfermería, 2018
Objective. The study sought to evaluate the effectiveness of an educational intervention based on cooperative learning on the acquisition of knowledge and skills on hand washing.
Teresa Dembilio-Villar   +3 more
doaj   +1 more source

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