Results 61 to 70 of about 1,843,245 (336)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

See No Evil, Print No Evil: The Criminalization of Free Speech in DMZ

open access: yesThe Comics Grid: Journal of Comics Scholarship, 2017
This article examines contemporary notions on free speech and the criminalisation of journalistic expression since 9/11, via discussion of Brian Wood’s DMZ comics (DC Vertigo).
Angus Nurse
doaj   +2 more sources

Economic evaluation: what does a nurse manager need to know?

open access: yes, 2005
This paper considers how health economists can assist nurse managers, using the concepts and tools of economic evaluation. We aim to clarify these and also explode some of the myths about economic evaluation and its role in health care decision-making ...
Douglas, Hannah-Rose, Normand, Charles
core   +1 more source

Systematic review and meta-analysis of patient reported outcomes for nurse-led models of survivorship care for adult cancer patients [PDF]

open access: yes, 2019
Purpose: This systematic review aimed to determine the effectiveness of nurse-led cancer survivorship care, compared with existing models of care, on patient reported outcomes for cancer survivors.
Berg, Melissa   +3 more
core   +2 more sources

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Decreasing Duration of Mechanical Restraint Episodes by Increasing Registered Nurse Assessment and Surveillance in an Acute Psychiatric Hospital [PDF]

open access: yes, 2018
Background Application of mechanical restraints is a high-risk emergency measure that requires psychiatric intensive care in order to assure patient safety and expedite release at the earliest opportunity.
Allen, Diane
core   +1 more source

Qualitative results from a phase II pilot randomised controlled trial of a lymphoma nurse-led model of survivorship care [PDF]

open access: yes, 2018
Purpose: To explore and describe lymphoma survivors’ thoughts and perceptions of the components of a nurse led lymphoma survivorship clinic intervention. Methods: An exploratory, qualitative descriptive study using interviews from 10 participants who had
Bulsara, Caroline   +2 more
core   +2 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Preliminary Effects of Low Intensity Exercise on Quality of Sleep, Activity of Daily Living, and Physiological Indicators of Kidney Function in Hemodialysis Patients

open access: yesNursing and Healthcare Science
Purpose: This preliminary study explored the effects of a 6-month low intensity exercise program on sleep, activity of daily living, physiological indicators in hemodialysis patients. Methods: A non-equivalent control group pre-post test design was used.
Kwi Kyung Kim   +6 more
doaj   +1 more source

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