Results 51 to 60 of about 26,772 (306)

Epstein‐Barr Virus Expressed Long Non‐Coding RNA (lncBARTs) Regulate EBV Latent Genome Replication

Advanced Science, EarlyView.
EBV produces abundant level of lncBARTs, which are essential for maintaining viral genome replication in EBV‐associated cancers. LncBARTs interact with a complex comprising BRD4, CTCF and viral protein EBNA1 at EBV oriP region. This interaction tethers oriP to host chromosomes, facilitating EBV episome replication.
Jiayan Liu, Dittman Lai‐Shun Chung, Larry Ka‐Yue Chow, Shuo Han, Wenkai Yi, Conor J. Cremin, Yingyin Liao, Pui Wang, Bobo Wing‐Yee Mok, Mingfang Ji, Jian Yan, Wei Dai, Honglin Chen   +12 more
wiley   +1 more source

Nursing Managers’ Coronary Care Unit Management Experience

Iranian Journal of Nursing and Midwifery Research
Background: The Coronary Care Unit (CCU) requires effective managers to consider- the patient’s acute condition. Studies have indicated that nursing managers of such units face many challenges. The purpose of the study is to explain nursing managers’ CCU
Azam Zare, Sima Mohammadkhan Kermanshahi, Zohreh Vanaki, Robabeh Memarian   +3 more
doaj   +1 more source

Regulating Tumor Metabolic Reprogramming with Biomimetic Co‐Delivery of Simvastatin and Kynureninase for Immunotherapy

Advanced Science, EarlyView.
After the intravenous injection of biomimetic and pH/ROS‐responsive PTSK@CRM, the nanoparticles can be accumulated in tumors and release Sim and KYNase to inhibit the tumor growth, regulate the metabolism of cholesterol and Kyn, and reverse the immunosuppressive tumor microenvironment.
Jiaxin Yin, Shengcai Yang, Zengguang Liu, Songchen Zhao, Siyu Sun, Ziling Liu, Quanshun Li   +6 more
wiley   +1 more source

The Clinical Supervision Process of Nurse Preceptors in Thailand: A Meta-Ethnography Research

Walailak Journal of Science and Technology, 2018
The purpose of this study was to synthesize five Graduate Theses on nurse preceptors by using Meta-Ethnography research method. The research finding fell into three steps as follows: Step 1 Preparing for teaching, Nurse preceptors prepared to their ...
Chawapon Sarnkhaowkhom, Ittipaat Suwathanpornkul   +1 more
doaj   +1 more source

Metformin Impairs Breast Cancer Growth through the Inhibition of PRMT6

Advanced Science, EarlyView.
Metformin has a biological activity against breast cancer. However, it is largely unknown about its precise therapeutic targets. Here, histone arginine methyltransferase PRMT6 is identified as a new anti‐cancer target for metformin. Metformin directly binds PRMT6 and inhibits its ability to catalyze histone H3R2 asymmetric dimethylation (H3R2me2a ...
Yinsheng Wu, Xinlin Xu, Yue Tong, Min Wang, Feng Ge, Min Wu, Yunlong Wang, Gang Chen, Xilan Yu, Shanshan Li   +9 more
wiley   +1 more source

Perspectives from Nurse Managers on Informatics Competencies

The Scientific World Journal, 2014
Background and Purpose. Nurse managers are in an excellent position for providing leadership and support within the institutions they serve and are often responsible for accessing information that is vital to the improvement of health facility processes ...
Li Yang, Dan Cui, Xuemei Zhu, Qiuli Zhao, Ningning Xiao, Xiaoying Shen   +5 more
doaj   +1 more source

Abusive supervision and turnover intention: Mediating effects of psychological empowerment of nurses

International Journal of Nursing Sciences, 2019
Objective: This study aims to determine the mediating effects of psychological empowerment on abusive supervision and turnover intention as perceived by nurses to provide information to change the status of nurse turnover.
Dongmei Lyu, Lingling Ji, Qiulan Zheng, Bo Yu, Yuying Fan   +4 more
doaj   +1 more source

An Automated Organotypic SCN Culture System Revealing Novel Insights into VIP Regulation of Circadian Rhythm

Advanced Science, EarlyView.
An Automated ex vivo culture system BaSIC, tailored for SCN slices and cell culture, which automates medium exchange and ensures a stable internal environment is developed. BaSIC enables real‐time observation of tissue/cell responses to diverse but programmed stimuli.
Kui Han, Meimei Liao, Jingpeng Zhang, Ruoyu Zhong, Long Mei, Dapeng Ju, Eric Erquan Zhang, Yanyi Huang   +7 more
wiley   +1 more source

Job Burnout of Nursing Administrators and Chief Executive Officers in University Hospitals and Its Relation to Their Demographic Features

مدیریت اطلاعات سلامت, 2011
Introduction: Job burnout results from the reaction to the chronic psychological stress and it mainly occurs in care services. It may lead to consequences such as job cost, reduced performance and fatigue.
Mandana Sahebzadeh, Saeed Karimi, Sayed Mohsen Hosseini, Ghazaleh Akhtar Danesh, Sahar Hosseini   +4 more
doaj  

Transplantation of GABAergic Interneuron Progenitors Restores Cortical Circuit Function in an Alzheimer's Disease Mouse Model

Advanced Science, EarlyView.
Transplantation of medial ganglionic eminence (MGE) interneuron progenitors into APP/PS1 cortices restored the slow oscillation characteristic of Alzheimer's disease. Donor cells survived, migrated, and matured into functional GABAergic interneurons, forming synaptic connections.
Shinya Yokomizo, Megi Maci, April M. Stafford, Morgan R. Miller, Stephen J. Perle, Shuzo Inagaki, Shusaku Takahashi, Heather Brown‐Harding, Linda Liang, Alex Lovely, Moustafa Algamal, Rebecca L. Gillani, Theodore J. Zwang, Douglas Richardson, Janice R. Naegele, Daniel Vogt, Ksenia V. Kastanenka   +16 more
wiley   +1 more source