Results 101 to 110 of about 844,807 (370)
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
Rankings Matter: Nurse Graduates from Higher-ranked Institutions Have Higher Productivity [PDF]
, 2017 Background Increasing demand for baccalaureate-prepared nurses has led to rapid growth in the number of baccalaureate-granting programs, and to concerns about educational quality and potential effects on productivity of the graduating nursing workforce ...
Weiss, Marianne E., Yakusheva, Olga
core +2 more sources
Molecular Oncology, EarlyView.TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik +3 more
wiley +1 more source
The flipped classroom: motivating student nurses to learn independently [PDF]
, 2015 The flipped classroom has become an internationally recognised teaching strategy in higher education institutions including those which deliver nurse education and training.
Davey, Philip
core
FEBS Open Bio, EarlyView.SLC7A11 frequently migrates faster in SDS‐PAGE. The present study found that the high hydrophobicity of SLC7A11 causes its anomalous migration in SDS‐PAGE with a low concentration of acrylamide gel. Replacing isoleucine with asparagine reduced hydrophobicity and restored its normal migration at 55 kDa, revealing the role of hydrophobicity and gel ...
Nsengiyumva Emmanuel +13 more
wiley +1 more source
Reflecting on the transition from practice to education : the journey to becoming an effective teacher in higher education [PDF]
, 2012 This paper discusses the journey of transition from practice to education by reflecting on the opportunities and challenges of this process. It utilises reflective principles to identify strategies for universities and the higher education sector to ...
Jones, Rebecca
core
Transient Dynamics of Infection Transmission in a Simulated Intensive Care Unit [PDF]
arXiv, 2019 Healthcare-associated infections (HAIs) remain a public health problem. Previous work showed intensive care unit (ICU) population structure impacts methicillin-resistant Staphylococcus aureus (MRSA) rates. Unexplored in that work was the transient dynamics of this system.
arxiv
Journal of Applied Clinical Medical Physics, EarlyView.Abstract The establishment of guidelines and curriculum standards for medical physics residency training is a critical component of setting expectations and competencies for the profession. Since the last publication of these standards, residency training has become integrated into the eligibility criteria for most medical physics certification bodies.
Jonathon A. Nye +16 more
wiley +1 more source
The burden of burnout: Understanding its prevalence and organizational drivers in medical physics
Journal of Applied Clinical Medical Physics, EarlyView.Abstract Background Burnout is a work‐related syndrome characterized by increased levels of emotional exhaustion (EE) and depersonalization (DP) along with decreased levels of personal achievement. In the healthcare setting, higher burnout levels have been associated with negative impacts on personnel, an increased risk of errors, and a decrease in the
Deborah Schofield +4 more
wiley +1 more source