Results 91 to 100 of about 917,136 (309)

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Assessment of Pain and Associated Comorbidities: A Survey of Real Life Experiences Among Nurses in Italy

Journal of Pain Research, 2021
Chiara Angeletti,1 Paolo Matteo Angeletti,2 Martina Paesani,1 Cristiana Guetti,3 Aglaia Gyra,2 Gianluca Perseo,1 Alessandra Ciccozzi,2 Franco Marinangeli,2 Emma Altobelli4 1Operative Unit of Anaesthesiology, Intensive Care and Pain Medicine, Civil ...
Angeletti C, Angeletti PM, Paesani M, Guetti C, Gyra A, Perseo G, Ciccozzi A, Marinangeli F, Altobelli E   +8 more
doaj  

Nursing education, virtual reality and empathy?

Nursing Open, 2020
An empathic approach to patient‐centred care is a core of nursing practice. One of the methods to develop empathy, which is gaining currency is the use of virtual reality simulations in education.
Sue Dean, Jodi Halpern, Margaret McAllister, Mark Lazenby   +3 more
doaj   +1 more source

The Association between the Competence, Motivation, Workload, and Performance of the Nurses at Dr. Arif Zaenudin Mental Hospital, Surakarta, Central Java [PDF]

, 2018
Background: Nurse performance in hospitals has an important role to support the achievement of good and satisfactory health services. The performance of nurses was hypothesized to be influence by several factors such as motivation, competence, and ...
Pundati, T. M. (Tia), Sulaeman, E. S. (Endang), Tamtomo, D. G. (Didik)   +2 more
core   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Developing a Business Case for the Care Coordination and Transition Management Model: Need, Metrics, and Measures [PDF]

, 2019
In this descriptive qualitative study, nurse and healthcare leaders\u27 experiences, perceptions of care coordination and transition management (CCTM®), and insights as to how to foster adoption of the CCTM RN role in nursing education, practice across ...
Brown, PhD, RN, CPHQ, FNAHQ, FAAN, Diane Storer, Conway-Phillips, PhD, RN, Regina, De La Pena, MSN, RNC, C-EFM, Laura, Haas, PhD, RN, FAAN, Sheila, Start, MSN, RN, NE-BC, Rachel, Swan, PhD, CRNP, FAAN, Beth Ann   +5 more
core   +1 more source

In the Spotlight [PDF]

, 2017
In September, 10 advanced practice nurses from the Department of Surgery gathered for a lunchtime kick-off meeting to form a Nurse Practitioners (NPs) & Physician Assistants (PAs) Professionalism and Scholarship Working Group.

core   +2 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Factors Contributing to Attrition of Nurse Educators at a Gauteng Public Nursing Education Institution, South Africa

SAGE Open Nursing
Introduction Addressing factors contributing to the attrition of nurse educators within the nursing education and training institutions is crucial because the problem affects the training of nurses globally. Public nursing education institutions in South
Daphney Mihloti Shirinda, Seani Adrinah Mulondo, Hilda Nwamuhohova Shilubane   +2 more
doaj   +1 more source