Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Pediatric Oncology Nurses’ Perceptions of Prognosis-Related Communication [PDF]
, 2019 Background Disclosure of prognosis-related information is an essential aspect of communication with pediatric patients with cancer and their families. The nurse is believed to play an important role in this process, but nurse perceptions and experiences ...
Haglund, Kristin +2 more
core +1 more source
Roles and functions of enrolled nurses in Australia: Perspectives of enrolled nurses and registered nurses [PDF]
, 2018 Aims and objectives: To determine, from the perspectives of enrolled nurses and registered nurses, the current scope of enrolled nurse practice and to identify the activities that most enrolled nurses frequently performed in their workplace.
Cross, W +8 more
core +2 more sources
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN PERILAKU PERAWAT TERHADAP PENERAPAN STANDAR ASUHAN KEPERAWATAN DI RSUD KABUPATEN SRAGEN [PDF]
, 2005 Mutu asuhan kepaerawatan sangat mempengaruhi kualitas pelayanan kesehatan dan bahkan sering menjadi salah satu faktor penentu citra institusi pelayanan dimata masyarakat.
SETYANINGSIH, HANUNG DWI
core
Nurses, computers and pre-registration education [PDF]
, 2009 Nursing informatics, the use of information and technology, to support the work of the nurse, is an essential part of the modern nurses’ job. In the UK this is supported by a range of National Health Service policy documents over the past decade ...
Bond, Carol S.
core +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Nursing ReportsBackground: Stress affects 45% of NHS staff. More research is needed to explore how to develop resilient mental health nurses who face multiple workplace stressors, including interacting with distressed clients. Higher Education Institutions are uniquely
Caroline Laker +2 more
doaj +1 more source
Caring attributes and preparedness to care: effects of a pre-enrolled nursing certificate programme in Singapore [PDF]
, 2014 Background: Caring is a highly complex and abstract concept, and nurturing a caring attribute among individuals for a nursing career is believed to be best introduced at the start of student journey in preparatory courses specifically designed for ...
Lee, Bryant +2 more
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School Nurses' perspectives on the role of the school nurse in health education and health promotion in England: a qualitative study. [PDF]
, 2016 BACKGROUND: The role of the school nurse is complex with many possible elements identified by previous research. The aim of this study is to understand perceptions of the role of the school nurse in order to support school nurses in the delivery of ...
Eley, CV +4 more
core +1 more source