Results 141 to 150 of about 2,810,960 (342)

What do managers’ know? Examining experienced managers’ wisdom [PDF]

open access: yes, 2015
Purpose: The paper critically examines the nature of managerial knowledge, highlights the limitations of formal managerial knowledge in informing managerial practice and demonstrates the role of alternative forms of knowledge, knowing and wisdom in ...
Black, Kate, Warhurst, Russell
core  

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

AUSPRAC : The Nurse Practitioner Research Toolkit [PDF]

open access: yes, 2010
Chapter 1: Introduction\ud \ud Overview and background\ud \ud Chapter 2: Conducting clinical audit of nurse practitioner practice \ud \ud The nature and purpose of clinical audit--\ud Data collection tools for clinical audit--\ud References and readings ...
Gardner, Glenn E.   +3 more
core   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Nurse Practice Act: Texas Statutes Regulating the Practice of Professional Nursing and Excerpts from the Board of Nurse Examiners' Rules and Regulations Relating to Professional Nurse Education, Licensure and Practice. As Amended 1991 [PDF]

open access: yes, 1991
Booklet issued by the Board of Nurse Examiners including the text of laws related to the regulation of the Board and various aspects of nursing licensure and ...
Texas. Board of Nurse Examiners.
core  

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

Investigating the impact of a leadership development program for nurse unit managers on the satisfaction of nursing staff [PDF]

open access: yes, 2013
Background and significance:\ud Nurses' job dissatisfaction is associated with negative nursing and patient outcomes. One of the most powerful reasons for nurses to stay in an organisation is satisfaction with leadership.
Fleming, Lesley Christine
core  

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

The lived experiences of clinical nurse managers regarding moral distress

open access: yesJournal of Medical Ethics and History of Medicine, 2018
Ethical management with minimum moral distress is one of the main duties of nurse managers. There is no doubt that a better understanding of the experiences of nurse managers in morally challenging situations could have an effective role in improving ...
Alireza Nikbakht Nasrabadi   +4 more
doaj  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

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