Results 121 to 130 of about 2,810,960 (342)

Nurse managers' explanation of Ubuntu characteristics

, 2023
This data was gathered through transcribed verbatim. Once the data was generated, the researcher conducted data analysis using thematic analysis (TA) to identify, analyse and report on themes within the data.
Thendo Mposi (14672999)
core   +1 more source

Knowledge sharing: nurse managers’ practices [PDF]

Revista Brasileira de Enfermagem
Objective: To analyze how management practices for sharing knowledge are developed in public hospitals in the context of nursing. Methods: Qualitative research, carried out with 15 nurse managers from six public hospitals, from July to September 2022 ...
Ana Lúcia Arcanjo Oliveira Cordeiro, Rosana Maria de Oliveira Silva, Josicélia Dumêt Fernandes, Gilberto Tadeu Reis da Silva   +3 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Management of resources during COVID-19 pandemic at an academic hospital in Gauteng, South Africa: nurse managers’ experiences

BMC Nursing
Background The onset of the COVID-19 pandemic required the mobilization of resources specifically for managing patients during the pandemic. The need for the mobilization of resources at the time of COVID-19 increased the nurse managers’ responsibilities
Kagiso Prince Tukisi, Mmaphala Mavis Matshidza, Jacobeth Mmabyala Louisa Malesela   +2 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Nurse Managers’ Talent Management and its Effect on Staff Nurses’ Engagement and Creativity [PDF]

Helwan International Journal for Nursing Research and Practice
Background: Nurse Managers’ talent management essential to increase the sense of belonging and loyalty to the organization, improve work relations, and provide a better understanding of what is happening in the organization all of this lead to improve ...
Dina Ali Mohamed
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Managerial Competencies of Nurse Managers in Ghana

, 2020
Managerial competencies of nurse managers are believed to influence the efficiency of healthcare. Amidst the global shortage of nurses and the rising cost of healthcare, it is imperative to assess the managerial competencies of nurse managers.
Adelaide Maria Ansah Ofei, Yennuten Paarima, Atswei Adzo Kwashie, Paarima, Yennuten, Kwashie , Atswei Adzo, Ofei, Adelaide Maria Ansah   +5 more
core   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source