Results 71 to 80 of about 2,699,017 (390)
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Facilitating the development of emergency nursing in Africa: Operational challenges and successes
African Journal of Emergency Medicine, 2021 The World Health Assembly declared 2020 as the ‘Year of the Nurse and the Midwife’ in recognition of the critical contribution of both professions to global health.
Petra Brysiewicz +3 more
doaj +1 more source
Acute care nurses' perceptions of barriers to using research information in clinical decision-making [PDF]
, 2002 Aim. To examine the barriers that nurses feel prevent them from using research in the decisions they make. Background. A sizeable research literature focusing on research utilization in nursing has developed over the past 20 years.
Cullum, N +4 more
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Training need assessment of nursing personnel as super specialty tertiary care hospitals in Northern India [PDF]
, 2015 Background - Super specialty tertiary care hospital equips nurses with the requisite knowledge and skills to deliver high quality care in their practice areas. This has necessitated adopting a structured approach to the training needs assessment (TNA) to
Arya, Sanjay +4 more
core +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Nursing satisfaction in caring for elders [PDF]
, 2012 Despite the increasing number of Americans who are over 65 years of age, little research exists about the satisfaction of nurses who care for this population.
Vlachos, Sarah L.
core +1 more source
The evidence-base for stroke education in care homes [PDF]
, 2008 <b>Summary.</b> <b>Research questions:</b> 1. What are registered care home nurses’ educational priorities regarding stroke care? 2. What are senior care home assistants’ educational priorities regarding stroke care? 3. How do
Craig, L.E. +3 more
core +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
International Journal of Nursing Studies AdvancesBackground: The burden of falls across the lifespan is substantial. Given the variety of clinical practice guidelines available for falls management, it is useful to understand the quality and clinical applicability of guidelines and their ...
Amber Harnett +6 more
doaj +1 more source