Results 241 to 250 of about 3,080,105 (382)

Navigating adverse immunostimulation: A practical guide for clinical researchers

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Problem Setting As drug development moves towards more complex products, early clinical development programmes are increasingly hampered by unwanted and/or unexpected activation of the immune system (adverse immune stimulation, AIS). Solution At the Centre for Human Drug Research, we have introduced standardized procedures to make AIS manageable, while
Juliette A. van den Noort   +3 more
wiley   +1 more source

Developing a Nursing Research Education Agent Using Knowledge Graphs and Large Language Models

open access: hybrid
Yingchun Zeng   +5 more
openalex   +1 more source

Risky or rigorous? Developing trustworthiness criteria for AI‐supported qualitative data analysis

open access: yes
Anatomical Sciences Education, EarlyView.
Michelle D. Lazarus   +4 more
wiley   +1 more source

Physiologically based pharmacokinetic model combined with a clinical lactation study to determine doravirine concentrations in human breastmilk

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims To determine breastmilk concentrations of doravirine via PBPK modelling in combination with a clinical lactation study. As women living with HIV are not able to cease antiretroviral therapy during lactation, it is necessary to establish drug transfer into breastmilk to determine exposure of the infant to antiretroviral drugs and potential risk of ...
Lena van der Wekken‐Pas   +3 more
wiley   +1 more source

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